Malignant Melanoma: Skin Cancer
Malignant melanoma is a condition where melanin-producing cells (melanocytes, pigment cells) become tumorous.
Melanin produced by these melanocytes absorbs ultraviolet (UV) radiation, thereby reducing cellular damage caused by UV exposure and preventing the development of malignant tumors, among other effects. The darkening of the skin from sun exposure is a result of melanocytes working to protect the skin from UV radiation.
However, when these melanocytes abnormally proliferate, it leads to malignant melanoma, also known as melanoma.
Among tumors, it is highly malignant and prone to metastasis.
Melanocytes are distributed in the skin, eyes, and mucous membranes, and malignant melanomas often develop in these areas. They are especially dense in parts that get a lot of sun exposure, like the face, or areas with physiological pigmentation, such as the external genitals.
Amelanotic melanoma refers to a type of malignant melanoma that does not produce melanin, and it is considered more malignant and has a poorer prognosis compared to typical malignant melanoma.
Malignant melanomas are more frequently observed in dogs (while relatively rare in cats), and like other tumors, the risk of occurrence increases with age. Breeds with a higher predisposition include Miniature Dachshunds and Labrador Retrievers.
Among tumors, it is highly malignant and prone to metastasis.
When surgery is feasible, it is the first treatment option.
However, depending on the location of the occurrence, complete removal may be difficult, leading to palliative surgery aimed at reducing volume, or it might require more extensive procedures such as jaw removal or limb amputation. Consequently, surgery might not be suitable for older pets, those in poor health, or those with metastatic sites.
Additionally, chemotherapy often yields limited results, and radiation therapy facilities are limited. Each session also necessitates anesthesia, raising concerns about its impact on the pet’s body.
In our laboratory, we are conducting research to determine whether administering Cordyceps can modulate the immune system and if it can be effective against cancer and melanoma.
If you have any questions, please contact us.
監修獣医師：林美彩 所属クリニック：chicoどうぶつ診療所
代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。 モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。
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