CBD stands for Cannabidiol, one of the natural phytocannabinoid compounds extracted from the stems and seeds of hemp (Cannabis sativa).

Not only humans but also dogs and cats have a system called the ECS (Endocannabinoid System) to maintain health.

The hormones involved in this system are called ‘cannabinoids.’ These cannabinoids decrease due to stress and aging, leading to ‘cannabinoid deficiency syndrome,’ which can cause various health issues.

Causes of Cannabinoid Deficiency Syndrome:
– Genetics
– Unbalanced diet
– Lack of exercise
– Poor sleep quality (e.g., short sleep duration)
– Overuse of medication
– Chronic stress

Main Symptoms Suspected in Cannabinoid Deficiency Syndrome:
– Excessive barking and fearfulness
– Restlessness
– Lack of energy
– Difficulty sleeping
– Pain
– Joint problems
– Skin issues

CBD is proposed as a supplement to these cannabinoids. By acting on the ECS, CBD helps maintain homeostasis, thereby maintaining health from the inside out. In other words, CBD helps restore the body and mind to their ‘natural state.’

The Difference Between CBD and THC:
Hemp contains more than 100 types of phytocannabinoid compounds. They can be broadly divided into two categories: CBD and THC (Tetrahydrocannabinol).

CBD is a component extracted from the stems and seeds of hemp. It interacts with neurotransmitters such as serotonin and dopamine in the brain, aiding in calming effects and stress relief. It is characterized by its lack of dependency and toxicity, offering deep relaxation. Over 1,000 studies have been conducted, revealing its efficacy for various symptoms. It is also used as a medication overseas.

On the other hand, THC is a component extracted from the flowers, buds, leaves, and roots of hemp that acts on the mind. When inhaled, it can make one feel “high,” leading to dependency and toxicity, hence its use is prohibited by law.

Some low-quality CBD products may contain trace amounts of THC. Using such products, even unknowingly, is illegal. It is recommended to inquire with manufacturers and ensure safety and quality personally.

Differences in CBD Manufacturing Methods:
CBD raw materials come in three types based on the manufacturing method: ① Full Spectrum, ② Broad Spectrum, and ③ Isolate.

① Full Spectrum
Most natural composition but may contain trace amounts of THC, which is regulated in Japan.

② Broad Spectrum
Contains a combination of cannabinoids other than THC, terpenes, and flavonoids, believed to offer a broader range of therapeutic effects. The synergy of these compounds is expected to result in higher efficacy, known as the ‘entourage effect.’ Products from the pet CBD manufacturer CANNNIMAL fall into this category.

③ Isolate
Contains no THC, making it the primary type imported into Japan. “Isolate” refers to extracting a single cannabinoid component from over 100 types and dissolving it in coconut oil or other oils. CBD alone or a combination of isolated components like CBG and CBN are offered.

Potential Benefits of CBD:
By incorporating the cannabinoids contained in CBD into the body, it is expected to regulate the ECS, helping to care for various ailments.

Foreign studies report potential applications for the following symptoms:
– Anxiety relief and reduction of anxious behavior
– Reduction of neuroses: anti-seizure effects, alleviation of epilepsy symptoms, neuroprotection, neurodegenerative diseases
– Brain ischemia (reduced blood and oxygen supply to the brain)
– Myocardial ischemia (reduced blood and oxygen supply to the myocardium)
– Inflammation
– Psoriasis
– Inflammatory bowel disease
– Arthritis and associated pain
– Inflammation suppression (cytokine release inhibition)
– Vomiting: chemotherapy-induced vomiting, motion sickness
– Type 1 diabetes, diabetic retinopathy
– Promotion of fracture healing and bone regeneration
– Cancer cells: Induction of apoptosis, inhibition of cancer cell proliferation, suppression/reduction of metastasis, mitigation of chemotherapy side effects
– Kidney protection (Cisplatin, used in chemotherapy, is highly toxic to the kidneys)
– Inhibition of drug-resistant bacteria activity

(Source: Izzo, et al. “Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.” Trends in pharmacological sciences 30.10 (2009): 515-527.)

While we cannot guarantee that it will be effective for every pet’s specific condition, this is an alternative therapy well worth trying for those who:
– Want to care for vague or general health issues
– Prefer not to use too many medications
– Are at a standstill with current treatments and are looking for other options
– Wish to alleviate stress

Feline AIDS is an illness caused by a virus called FIV (Feline Immunodeficiency Virus).

When a cat infected with the FIV virus develops AIDS, it falls into immunodeficiency, increasing susceptibility to various diseases. However, we believe that by undertaking immune system measures, it is possible to improve the cat’s condition, maintain quality of life (QOL), and restore vitality and appetite.

At the Cordy Research Lab, we are studying whether immune measures can help maintain the health of cats that have developed feline AIDS, and there are numerous cases where the condition has stabilized.

This page summarizes the causes, symptoms, treatments, and tips for improvement and cure of feline AIDS and FIV. Examples of improvement are also introduced. We hope it will be a support of hope and light for you all.

What is Feline AIDS?

Improving Kidney Failure and Kidney Disease

Kidney function often declines or ceases to work in older cats.

Damaged kidneys do not recover.

Therefore, to prevent the progression of kidney failure symptoms, it is important to maintain the remaining kidney functions and reduce the burden on the kidneys.

Administering IV or subcutaneous fluids helps promote the elimination of toxins, aiming to alleviate symptoms and improve kidney function.

For pre-renal or post-renal cases, it is also crucial to treat the underlying disease causing the condition.

To slow the progression of kidney failure, it is important to care for the kidneys and maintain physical strength along with treatments at the animal hospital.

Here are some recommended methods you can implement at home.

If your pet’s energy and appetite recover, it means your efforts are paying off.

If you have any questions about Cordy, EPA/DHA, BCAA (amino acids), or green tripe (ruminant stomach), please feel free to contact us.

Contact us here

Kidney Failure and Kidney Disease in Dogs and Cats

This disease can occur in both dogs and cats, but it is more common in cats. According to overseas reports, 30% of cats over the age of 15 have chronic kidney failure.

One reason why cats are more prone to kidney failure is believed to be due to their lower water intake, which places a burden on their kidneys to concentrate urine, making them more susceptible to kidney disease as they age.

Additionally, a 2016 study suggested that a special protein called “AIM” does not function adequately in cats’ kidneys, which may predispose them to chronic kidney disease.

In humans, dogs, and cats, kidneys function like coffee filters.
They filter and remove waste products and excess salts from the body, reabsorb what is necessary, and produce urine to regulate the body’s fluid balance. When the kidneys stop working, waste accumulates in the body, leading to various symptoms.

When waste and toxins are not effectively excreted, conditions such as ‘uremia‘ and ‘hyperkalemia‘ can develop.

Like the liver, the kidneys are called the “silent organs,” and it is believed that by the time abnormalities are detected in blood tests, more than 70% of the kidney function is already lost.

In humans, dogs, and cats, once the kidneys stop working (or are damaged), they do not recover, so reducing the damage to the functioning kidney cells is the key to managing kidney failure effectively.

Although kidney failure is a challenging disease to control, with dietary therapy and treatment to reduce the burden on the kidneys, pets can enjoy a peaceful life in their remaining years.

Types of Kidney Failure

Kidney failure is classified into three types depending on the location of the impairment.

The kidneys are rich in blood vessels, and renal failure can occur when there is an issue in the vascular system before it reaches the kidneys, causing a change (decrease) in the blood flow to the kidneys.
Causes of prerenal failure include dehydration, anemia, heart failure, endocrine disorders, and heartworm disease.

② Renal
This refers to renal failure that occurs when there is a problem within the kidneys themselves.
Causes include parasites, infections, trauma, tumors, and drug toxicity.
Congenital abnormalities (inborn defects) are also included.

③ Postrenal
This refers to renal failure caused by abnormalities in the urinary tract system after it exits the kidneys.
Causes include urolithiasis (urinary stones/bladder stones), bladder tumors, and urination disorders.

Renal failure can also be classified into two types based on the progression: acute and chronic.

Symptoms of Renal Failure

In acute cases, symptoms such as loss of appetite, vomiting, diarrhea, and lethargy are observed.

Some animals may cry out or become more aggressive due to kidney pain.

In chronic cases, due to the slow progression, noticeable symptoms may not be present, but in general, there is an increase in water intake and urination.

Additionally, characteristic bad breath (ammonia odor), anemia (due to decreased production of erythropoietin stimulated by kidney impairment), and constipation due to dehydration may also be observed.

As renal failure progresses and uremia develops, neurological symptoms such as seizures and coma may also occur.

Diagnosis

High values of BUN (blood urea nitrogen), Cre (creatinine), and IP (phosphorus) can be detected in blood tests, along with low values in the red blood cell parameters.
(Abnormalities in other parameters may also be seen)

In urine tests, renal failure is diagnosed by referencing values such as urine specific gravity, UPC (urine protein/creatinine ratio), and UAC (urine albumin/creatinine ratio).

Renal failure is classified using the ‘IRIS classification,’ which provides an estimate of remaining kidney function based on the stage.

In addition, since 2015, a new test called ‘SDMA’ has been introduced by Idexx, allowing for early detection of chronic kidney failure. It is recommended to include this test in the evaluations. Other diagnostic methods may include X-rays, ultrasound, contrast studies, and blood pressure measurement.

Treatment Methods

In cases of prerenal or postrenal conditions, it is also important to treat the underlying diseases causing the issue. In acute renal failure, the rapid worsening of symptoms can be fatal, requiring immediate treatment.

If treatment is delayed or the kidney damage is extensive, the condition might progress to chronic kidney failure.

In the case of chronic kidney failure, besides IV infusions, diet changes, oral medications, and injectables can be employed to slow down the decline in kidney function and control the worsening of symptoms.

Pitfalls of Kidney Prescription Diets

When kidney values are higher than the standard range, it is generally recommended to switch to a prescription diet.

The contents of prescription diets are designed to reduce the load on the kidneys, meaning they consist of foods that generate fewer waste products and therefore have a low protein content.

However, considering that dogs and cats are originally carnivores (especially cats, which are obligate carnivores), reducing protein too much can lead to energy deficiency. Even if kidney metrics improve, many pets may still lack stamina and vigor.

Indeed, there is no clear evidence that protein restriction in cats with kidney disease can prevent the progression of the disease.

Hydration

It is recommended to switch from dry food to wet food or provide homemade meals with plenty of broth.

Appropriate Protein Levels

Since the ability to process proteins varies among pets, try slightly lower-protein food compared to what you are currently using. Regular blood tests can help monitor kidney metrics and determine the appropriate protein level for your pet.

High-Quality Proteins

The closer the amino acid score is to 100, the fewer waste products are produced when the proteins are broken down, meaning less burden on the kidneys. However, foods with high amino acid scores (meat, fish, eggs) are also high in protein, so start with small amounts when introducing them.

For pets with impaired kidney function, providing essential amino acids such as BCAAs can help improve symptoms.
Additionally, green tripe, which is the stomach of ruminant animals, is also recommended.

Increasing Lipid Intake

Reducing protein intake can lead to an overall energy (calories) deficiency. If energy deficiency persists, the body’s own protein (such as muscles) will be utilized, resulting in the production of a lot of waste products.

To prevent this, energy must be supplemented through carbohydrates and lipids. However, both dogs and cats are not very good at breaking down carbohydrates. Particularly in cats, many have intolerance to grains and are better at metabolizing lipids than carbohydrates.

While there are various types of fats, for renal failure where kidney inflammation may be present, Omega-3 fatty acids are recommended to reduce inflammation.

Sources of Omega-3 fatty acids include plant-derived flaxseed oil and perilla oil, and animal-derived EPA and DHA. Although plant-derived Omega-3 fatty acids can be converted by enzymes in the body to the animal-derived form with anti-inflammatory and anti-tumor effects, some dogs and cats may not have these enzymes work effectively.

For a direct and effective form, it is recommended to use krill oil (EPA/DHA from Antarctic krill).

*Excessive fat intake can burden the pancreas and potentially cause pancreatitis, so start with small amounts.

Currently, our research laboratory is investigating whether the immune-regulating functions of Cordyceps can aid kidney function.

Prevention Methods

Unlike us, it is challenging to encourage dogs and cats to drink water actively. Cats, in particular, tend to consume less water compared to dogs, as their ancestors lived in the desert.

Additionally, many pets nowadays are fed dry food, leading to virtually zero water intake from their diet.

Moreover, simply increasing the amount of water intake is not meaningful unless the pet properly urinates to expel waste.

Some types of dry food contain high amounts of salt to make them more palatable for dogs and cats. Inferior quality foods especially tend to have higher salt content, and such foods generally also have a wealth of additives such as flavorings.

Reducing the intake of high-salt foods can lessen the burden on the kidneys. Therefore, it is advisable to limit treats like jerky, dried bonito flakes, and dried sardines.

If you are using commercial pet food, please check the ingredients and nutritional information thoroughly before purchasing. For early detection of issues, regular blood tests and urine tests are recommended once your pet reaches their senior years.

Additionally, in the case of cats, they may avoid using the litter box if it is dirty.

Holding in their urine can lead to kidney strain, so maintaining litter box hygiene is also important.

Cats often develop kidney failure around the age of 6 years. Therefore, it is crucial to monitor any changes in their daily water intake and urination.

A decline in immune function can also affect the kidneys.

The immune system is an important factor for maintaining overall body balance, and its decline can not only lead to kidney failure but also other diseases.

For pets to lead as healthy and peaceful lives as possible, regular care is essential. The supplement Cordy is expected to help maintain health by restoring the body’s natural immune regulation.

For pets like dogs, cats, and even exotic animals suffering from tumors or other diseases, Cordy may help reduce the side effects of aggressive treatments and support the maintenance of quality of life in cases where there are few other treatment options.

There are also cases where the promotion of blood flow by organic germanium in Cordy has led to improved kidney function indicators.

If you have any questions, please feel free to contact us.

・Nowadays, the leading cause of death in cats is said to be cancer, and when limited to older cats, about half die from cancer

・There are mainly nine causes of cancer in cats, with aging being the primary cause

・Early detection of cancer in cats is crucial, so their symptoms need to be closely monitored

・Even after being diagnosed with advanced cancer or given a terminal prognosis, efforts to boost immunity can improve the cat’s condition, maintain their quality of life (QOL), and help them regain their appetite and vitality

Request free information about Cordy treatment>>

What is cat cancer?

Early detection of cancer in cats is crucial, but it’s even more important to create a living environment that reduces the risk of cancer and to take steps to support the immune system, which can help prevent cancer from developing in the first place.

As some of you may already know, both humans and cats develop cancer cells in their bodies daily. However, if a cat’s immune system is functioning well and the balance of hormones and the autonomic nervous system is maintained, these cancer cells are less likely to grow and form into cancer.

Even if cancer has already developed, understanding its causes and eliminating them as much as possible can help create an environment where the cancer is less likely to grow or spread.

To achieve this, it is crucial for cat owners to learn accurate information about cat cancer.
Why not study together for the sake of your beloved cat?

Main Types of Cancer in Cats – What kind of cancer can cats get?

Below are some of the representative tumors (cancers) that can occur in cats.

Cancers on the Skin, Body Surface, and Oral Cavity

Squamous Cell Carcinoma in Cats

Squamous Cell Carcinoma in Cats is a skin cancer that frequently occurs in middle-aged and older female cats, and those with white fur.

Squamous cell carcinoma in cats often develops in the mouth, around the eyes, nose, and mouth, but since it can occur in any area where squamous cells are present, it is one of the malignant tumors that can appear on the entire skin, around the nails, and the abdomen.

The majority of oral tumors (tumors inside the mouth) in cats are believed to be this squamous cell carcinoma.

Mast Cell Tumor in Cats

The second most common cancer that occurs on the skin of cats is the Mast Cell Tumor.

Mast cell tumors are malignant tumors that arise from mast cells, which are responsible for immune responses, but they are not related to obesity.

There are “cutaneous mast cell tumors,” which occur on the skin around the head and neck, and “visceral mast cell tumors,” which occur in internal organs such as the spleen, liver, and small intestines.

Malignant Melanoma (Melanoma, Skin Cancer)

Melanoma in Cats commonly occurs in cats over nine years old and is especially prevalent in black-colored cats.

Melanoma, also known as malignant melanoma, is a type of skin cancer that progresses rapidly and is prone to recurrence and lung metastasis, making it one of the most dangerous types of cancer.

Other cancers that frequently develop on the skin, body surface, and in the oral cavity include Fibrosarcoma and Soft Tissue Sarcoma.

Cancers Commonly Found in Internal Organs

Mammary Tumors in Cats

Mammary tumors are commonly referred to as breast cancer.

Mammary tumors are highly recurrent carcinomas in cats and are considered difficult to completely cure.

Feline Lung Cancer and Lung Tumors

Primary lung cancer and lung tumors in cats are not very common cases. The incidence rate of lung cancer is less than 1% of all cancers, making it a rare type of cancer.

Feline Hepatocellular Carcinoma and Liver Cancer

Cancer that develops in the liver is called liver cancer. Liver cancer includes primary liver cancer, where liver cells, or stem cells, become cancerous, and metastatic liver cancer, where cancer has spread to the liver from other areas.

Feline Hemangiosarcoma

Hemangiosarcoma is a type of cancer (malignant tumor).

Since it develops in the endothelium of blood vessels, it is commonly seen in organs with abundant blood vessels like the liver and spleen. Hemangiosarcoma is rare in cats, but its prognosis is extremely poor and it is considered difficult to cure once it develops.

Feline Malignant Lymphoma

Lymphoma in cats varies in type depending on the site of occurrence.

Transitional Cell Carcinoma / Bladder Cancer in Cats

Most bladder cancers in cats are transitional cell carcinomas that originate from the transitional epithelium.

Other cancers include soft tissue sarcoma, perianal gland carcinoma, histiocytic sarcoma, brain tumor, osteosarcoma, basal cell carcinoma, and ovarian cancer.

9 Causes of Cancer in Cats

In addition to aging, other causes of cancer include a weakened immune system due to stress, chronic inflammation, lifestyle habits (such as diet), infections by viruses (like Feline Leukemia Virus (FeLV), Feline Immunodeficiency Virus (FIV), retroviruses, papillomaviruses, etc.), genetic factors, radiation, chemical substances like food additives, pesticides, insecticides, and tobacco, and in some cases, hormonal influences (such as mammary tumors, perianal gland tumors, and prostate cancer).

Main causes of cancer in cats include:

Weakening of the Immune System

Cancer and the immune system are closely related. This holds true for cats as well.

It is inevitable that cells will make errors (abnormalities) due to various reasons. Normally, when abnormal cells develop, the immune system recognizes, attacks, and eliminates these cells in a series of reactions, preventing cancer from growing unchecked.

Conversely, even if cancer develops, regaining immune function can help in controlling its growth.

Providing emotional care is one method to prevent the worsening of cancer.

Aging

Aging is a major risk factor for cancer development in both cats and humans. One reason for the significant increase in cancer rates in cats is their increased average lifespan.

As they age, their immune system weakens, making it more challenging to successfully complete the series of actions needed to identify, attack, and eliminate cancer cells, thus increasing the likelihood of developing cancer. It is recommended to incorporate immune support measures as your beloved cat reaches middle to senior age.

Genetics

There are genetic factors contributing to cancer in cats. However, acquired factors (post-birth) tend to have a greater impact than congenital (inherited) ones, so it is important to provide a proper diet and environment for your pet.

Chemicals

Chemicals, including pesticides, increase the incidence of cancer in cats.
Please try to minimize the exposure to chemicals as much as possible.

Tobacco Smoke (Secondhand Smoke)

While cats do not smoke, they may develop cancer due to secondhand smoke if any family members smoke. Since tobacco smoke contains many carcinogens, it is important for smokers to smoke away from cats.

Chronic Inflammation

Chronic inflammation can stimulate cells and make it easier for cancer cells to develop. It is recommended to identify and eliminate the causes of inflammation, enhance the immune system, and appropriately provide oils such as EPA and DHA, which have anti-inflammatory effects, to reduce inflammation.

Hormones

Certain cancers, such as mammary tumors (breast cancer) and prostate cancer, are influenced by hormones.

Viruses

Infection with viruses can lead to chronic inflammation and the potential for cancer. Because a strong immune system can eliminate viruses, it is essential to boost your cat’s immune system regularly.

Obesity

Obesity can lead to various diseases, including cancer, heart disease, arthritis, and diabetes. High carbohydrate intake can easily lead to obesity, so it is important to pay attention to your cat’s daily diet.

Symptoms of Cancer in Cats

If you notice any of the following symptoms, your cat may have cancer, and it is advised to visit a veterinary clinic as soon as possible to determine the cause of the symptoms. Cancer becomes more difficult to treat as it progresses, so it is important to pay attention to any changes in your cat’s health regularly.

It is rare, but sarcomas can develop at the injection sites of vaccines or antibiotics.

=> Injection-Site Sarcomas in Cats: Treatment, Improvement, and Healing Tips

Nine Symptoms Caused by Cancer

Here are nine common symptoms that may appear depending on the location of the cancer. Please refer to this list for guidance.

Common Symptoms of Oral Cancer

Types of oral cancer that are likely to develop include:

You may notice changes such as decreased appetite, bad breath, or bleeding from the mouth or surrounding area.

In advanced or terminal cancer stages, solid foods may become difficult to consume, tumors may become noticeable, and metastasis to the lungs may cause labored breathing or coughing.

Symptoms of Superficial or Skin Cancer

Common types of cancers that develop on the surface or skin include:

You might notice lumps or nodules. Skin layers may ulcerate and cause bleeding.

As cancer progresses and metastasizes to the lungs or liver, symptoms such as coughing, fatigue, and ascites (fluid accumulation in the abdomen) may manifest.

Cancers on the skin’s surface are often detected sooner than those on internal organs.

If you notice anything unusual, it is recommended to visit a veterinary hospital as soon as possible.

Common Symptoms of Respiratory Cancer

Respiratory-related cancers, such as those in the lungs or nasal cavity, include:

In many cases, there are no symptoms in the early stages.

As the cancer progresses, symptoms such as rapid (or labored) breathing, frequent coughing, and blood-tinged sputum may appear.

Common Symptoms of Visceral or Digestive Cancer

While it may be difficult to detect visceral cancer in the early stages, symptoms such as loss of appetite, weight loss, vomiting, and diarrhea may appear.

If these symptoms occur, it is advisable to consult a veterinarian promptly.

Common Symptoms of Bladder and Urinary Tract Cancer

Bladder cancer, transitional cell carcinoma, and cancers around the anus include:

If these cancers emerge, symptoms such as difficulty urinating, difficulty defecating, blood in the urine, or blood in the stool may occur.

Common Symptoms of Liver Cancer

As mentioned above, there are primary and metastatic liver cancers. Primary liver cancers include “hemangiosarcoma” and “hepatocellular carcinoma.”

As you may know, the liver is often referred to as the “silent organ,” meaning it may be difficult to detect liver cancer in your beloved cat.
The liver generates energy and breaks down toxins, but these functions decline when it becomes cancerous.

As a result, symptoms like “lethargy,” “appearing listless,” “decreased appetite,” and “(in some cases) jaundice or ascites” may appear.

Cancer Treatment in Cats

Here is a summary of cancer treatments for cats that you can use as a reference.

Upon a cancer diagnosis, treatments generally include “surgery,” “chemotherapy,” “steroids and antibiotics,” and “radiation therapy (in well-equipped hospitals).”

Surgery

The benefit of surgery is that it can simultaneously remove the cancer, surrounding tissues, and lymph nodes where metastasis may have occurred.

A surgery that aims to remove all observable cancer is known as an excision surgery.

If the cancer has not metastasized and remains localized (low invasiveness), this treatment can potentially lead to a cure.

On the other hand, even when complete removal of cancer is difficult, surgery may be performed to alleviate symptoms and improve the quality of life (QOL). This is referred to as a palliative surgery.

The drawbacks of surgery include the necessity of general anesthesia, the significant physical burden on the body due to incisions, and the potential for post-operative complications, including loss of organ function depending on the site of excision.

Additionally, if the cancer has extensively metastasized, it becomes challenging to completely remove it through surgery.

Radiation Therapy

Radiation therapy involves using radiation to destroy cancer cells.
General anesthesia is required to keep the cat still during the procedure.

Unlike surgery, radiation therapy has the following benefits:

However, there are also disadvantages to radiation therapy, including:

Chemotherapy

The basic concept of chemotherapy involves introducing strong toxins (chemotherapeutic agents) into the body to kill cancer cells.

The benefits of chemotherapy include:

There are other advantages as well.

As for the disadvantages:

There are other disadvantages as well.

If your beloved cat has been recommended for chemotherapy or is already undergoing it, please read the following articles.

By understanding the benefits and drawbacks of chemotherapy, we hope you can consider whether receiving or discontinuing chemotherapy is the best course of action for your cat, taking into account the state of their cancer and their overall strength.

Common Metastasis Sites – Locations Where Cancer Spreads in Cats

As cancer progresses, it can infiltrate the lymphatic and blood vessels, spreading throughout the body via the lymph fluid and bloodstream.

Additionally, cancer prefers an oxygen-deprived environment and lower body temperatures.

Both humans and pets like dogs and cats circulate blood to deliver oxygen throughout their bodies and maintain their body temperatures.

Thus, when the body becomes cold or the blood flow (circulation) is poor, cancer tends to metastasize more easily.

Lymph nodes are stationed along the lymphatic vessels, acting like checkpoints where lymph fluid from all body tissues passes through.

Moreover, organs like the liver, lungs, bones, and brain have a large blood supply but are also areas where blood flow can stagnate.

Consequently, lymph nodes, liver, lungs, bones, and brain—areas where lymph fluid and blood tend to accumulate—are common sites for cancer metastasis.

To effectively manage cancer, it’s crucial to focus on keeping the body warm and improving blood circulation for these reasons.

Mindset When Your Beloved Cat is Diagnosed with Cancer

When your beloved cat is diagnosed with cancer, it’s natural for the owner to be shocked.

However, depending on our approach, it is possible to control the progression of cancer and maintain your cat’s energy and appetite.

If the owner feels down or becomes irritable, the cat might sense that it’s causing distress to their beloved owner.

Therefore, instead of looking back in regret or worrying about why the cancer occurred, think about what you can do to keep your cat as spirited and happy as possible.

Starting After Accepting and Resolving to Battle Cancer – Feline Cancer

A strong will from the owners is required to keep smiling even when your beloved cat is diagnosed with cancer.

Our company provides tips on the necessary mindset, immune-boosting methods, nutritional strategies, and more to help cats coexist with cancer while maintaining their energy and appetite.

Cancer is not like an accident or injury that immediately threatens life.

Even if your beloved cat is suffering from cancer, it is possible to coexist with it.

Once the owner resolves to fight for their beloved family member against cancer, please enjoy more communication with your cat and spend as much time together as possible.

And to coexist with cancer, please start as soon as possible the practices that you and your family can undertake at home.

As detailed further, the methods you can practice at home aim to boost physical strength and immunity and combat cancer without taking away the enjoyable time with your cat.

Concept of Feline Cancer Treatment

Understanding the Reality of Feline Cancer Treatment

Regrettably, with current veterinary medicine, it is challenging to consistently control cancer, except in its early stages.

Even if a tumor is thought to be entirely removed through surgery in the early stages of cancer, it is not rare for it to recur or metastasize.

Moreover, many veterinarians believe that the prognosis is poor if cancer recurs or metastasizes.

While veterinary medicine and feline cancer treatment are advancing, at present, it remains difficult to completely eliminate all cancer cells or destroy them without leaving any traces, regardless of the excellent treatment methods available.

For example, even in malignancies like lymphoma, which are said to be most responsive to anti-cancer agents, cases of recurrence after remission are not uncommon.

Many cats experience recurrence despite successful surgeries that completely excised the tumor.
Adding chemotherapy after surgery to prevent recurrence is not uncommon, but recurrence can still occur.

Therefore, rather than relying solely on conventional cancer treatments, I believe it is necessary to start complementary and alternative efforts to overcome cancer.

Changing the Way You Think About Cancer

It is difficult to completely eradicate or remove cancer, and doing so places a significant burden on the body.

However, with the perspective of “controlling the growth of cancer” and “maintaining energy and appetite even if cancer remains in the body,” the goals become more achievable without placing a heavy burden on the body.

Thinking about “coexisting with cancer” is also a viable approach.
At our company, when cats become ill, we aim to extend their lives in a way that allows them to stay as healthy and happy as possible, enjoying their meals. Even if this goal isn’t entirely achievable, we hope it will still provide a sense of happiness for their owners.

If Your Beloved Cat is Diagnosed with Terminal Cancer

What to Confirm Before Undergoing Chemotherapy

Hearing from a veterinarian that your cat has “terminal cancer” and “only 1–2 months to live without treatment” can be devastating, making you feel the only option is to rely fully on the veterinarian.

However, do not give up even if your cat is diagnosed with terminal cancer. The effort of the owner can greatly influence the treatment outcome and significantly affect the prognosis.

If you feel the disadvantages of chemotherapy outweigh the benefits, consider the courageous choice of “not undergoing chemotherapy treatment.”

Using Immunity to Fight Cancer

Our company aims to enhance a cat’s vitality and immune strength without burdening them, with the objective of combating or coexisting with cancer. While we can’t guarantee 100% positive results, at least it will not place a burden on the body, and you can assess its effectiveness in a short time.

Here are the key recommended efforts:

It is very important to avoid imposing physical and mental stress on the animals as much as possible. Both physical and mental stress can exacerbate cancer. Therefore, I believe we should actively incorporate efforts that do not burden the cat physically or mentally, and that have evidence and successful track records.

Revisiting the Diet

Cancer grows by feeding on glucose. Changing the diet alone might not cure cancer, but reducing glucose intake through diet changes is seen as essential for managing cancer effectively.

Additionally, I have compiled information about diets that help improve your cat’s condition, so please take a read. Especially for cats with kidney issues, which is not uncommon, it is recommended to provide “appropriate protein” instead of the therapeutic diets for kidney disease if you want a high-protein diet. Administering BCAAs can also help restore kidney function.

Efforts to Improve Immunity

When starting chemotherapy, physical strength and immunity are almost certain to decline.

If your dog’s physical strength and immunity decrease, their quality of life (QOL) will decline. Even if treatment extends their life somewhat, it may only increase the time they spend suffering from cancer.

Therefore, to maintain physical strength and immunity, first provide good nutrition to build stamina to avoid retiring due to treatment side effects. Ensure that immunity is not compromised.
In fact, immunity is the primary factor in cancer suppression, while chemotherapy is merely supplementary.

Cordy allows for immune support without placing strain on the body.

There is potential to cherry-pick the best elements from various treatments.
Sole reliance on chemotherapy is clearly insufficient. It is essential to combine complementary treatments to create a balanced approach.

To Undergo Treatment Without Regrets

We have compiled information that we want to share with owners whose cats have been diagnosed with cancer.

We do not want owners to regret anything. We want them to avoid later lamenting their choices.

Whether to undergo treatment, surgery, chemotherapy, or radiation, or to consider avoiding treatment considering the physical burden—there is no definitive answer for cancer treatment.
Conversely, any choice the owner makes out of love for their cat is the right choice.

However, it is not advisable to solely rely on doctors or give up.
Instead of depending entirely on surgery or chemotherapy and leaving everything up to the veterinarian, we want you to know there are many things you can do at home with your family.

When your cat is suffering from cancer, it is crucial to undertake immune support, regardless of whether treatment is undergone.

At our laboratory, we are continuing research to see if administering Cordy during immune suppression will hasten immune recovery.

While we cannot predict how much response or improvement there will be, there is a good possibility that appetite will increase and energy will be regained.

Using medications such as chemotherapy, steroids, and antibiotics comes with a concern for liver function decline.
In such cases, combining treatment with Domestic SPF Pig-Derived Placenta Extract may help minimize liver damage.

Even in cases where liver values have already deteriorated, there are many examples where liver function improves within about a month with the administration of Domestic SPF Pig-Derived Placenta Extract.

Additionally, since cancer is often accompanied by inflammation, it is believed that giving EPA/DHA Krill Oil Extracted from Antarctic Krill with anti-inflammatory properties may also be effective.
Our laboratory is continuing research on Cordy, which is expected to have immune-modulating properties, domestically produced SPF pork-derived placental extract, which is expected to protect liver function, and krill oil, which is expected to have anti-inflammatory properties. If you have any questions, please feel free to contact us.

Consult (free of charge) about pet illnesses and Cordy treatment >>

Request materials on Cordy treatment (free of charge) >>

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

“`json
{
“@context”: “https://schema.org”,
“@type”: “FAQPage”,
“mainEntity”: [
{
“@type”: “Question”,
“name”: “What is cancer in cats?”,
“acceptedAnswer”: {
“@type”: “Answer”,
“text”: “Cancer, known as a malignant tumor, can occur in cats just as it does in humans. In recent years, cats’ lifespans have increased, but on the other hand, cancer incidence rates have surged, particularly in older cats. Nowadays, cancer is said to be the leading cause of death in cats. Especially in elderly cats, cancer (malignant tumors) is the top cause of death, with approximately half of them dying from cancer.”
}
},
{
“@type”: “Question”,
“name”: “9 causes of cancer in cats”,
“acceptedAnswer”: {
“@type”: “Answer”,
“text”: “• Decreased immunity due to stress, aging, genetic factors, and chemical substances (such as pesticides, herbicides, insecticides, and food additives) • Tobacco smoke, chronic inflammation • Hormonal relations (such as mammary gland tumors, perianal gland tumors, prostate cancer) • Viruses • Obesity • Injections like vaccines and antibiotics”
}
},
{
“@type”: “Question”,
“name”: “Symptoms that appear when a cat has cancer”,
“acceptedAnswer”: {
“@type”: “Answer”,
“text”: “• Decreased energy and appetite • Sudden weight loss • Loss of vitality • Lumps on the body surface • Hard areas when touching the body • Bleeding from the mouth, nose, or anus • Swollen lymph nodes • Strong body odor or bad breath • Not neutered/spayed • Persistent vomiting or diarrhea • Persistent coughing • Severe dermatitis • Difficulty urinating, frequent urination, bloody urine • Seizures or epilepsy symptoms • Accumulation of ascites • Jaundice”
}
}
]
}
“`

In fact, there are numerous cases where cancer has been successfully controlled.

This page details common cancers in dogs, their causes, symptoms, treatments, what to prepare for if your dog is diagnosed with cancer, how to cope with it, and tips for living comfortably even with cancer.

Whether your dog is about to undergo surgery or chemotherapy, is currently undergoing treatment, cannot continue treatment anymore, or has been given a terminal diagnosis, this page can be of help to you.

We also feature numerous improvement cases. We hope this can be a source of comfort and a beacon of hope for you.

Symptoms That May Appear When a Dog Has Cancer

If your dog exhibits any of the following symptoms, it may be suffering from cancer.

It is recommended to visit a veterinary hospital as soon as possible to determine the cause of the symptoms showing in your dog.

Especially in advanced stages of cancer, various symptoms may appear. Please be attentive to any changes in your dog’s condition.

The symptoms can vary greatly depending on the location of the cancer. Below, we will explain the main types of cancer and their symptoms.

The Six Most Common Types of Cancer (Malignant Tumors) in Dogs

The most common types of malignant tumors (cancers) found in dogs include the following.

Oral Cancer

When cancer occurs in a dog’s oral cavity, it can lead to severe bad breath, pain, difficulty eating which results in decreased appetite, and visible changes in appearance. The main types of oral cancer include:

Some dogs may not want to show the inside of their mouths, but as the cancer progresses to advanced or terminal stages, symptoms such as being unable to eat solid foods, noticeable tumors, metastasis to the lungs causing labored breathing, and coughing may occur.

Cancer of the Body Surface and Skin

When cancer progresses, it can metastasize to the lungs or liver, leading to symptoms like coughing, fatigue, and fluid accumulation in the abdomen.

Cancers on the body surface are often noticed before they reach an advanced stage.

When cancer appears on a dog’s body or skin, you might notice a hard lump.

If you feel anything unusual while petting your dog, it is recommended to consult a veterinary clinic as soon as possible.
In addition, within the nasal cavity, conditions such as Intranasal Tumor and Nasal Adenocarcinoma in Dogs can develop.

Malignant tumors around the anus include Apocrine Gland Adenocarcinoma of the Anal Sac. Likewise, around the anus, there is a benign tumor known as Perianal Adenoma.

Respiratory Cancers

When nasal cancer develops, symptoms such as “rapid and heavy breathing,” “frequent coughing,” and “coughing up blood-tinged sputum” may appear.

Respiratory cancers may not be noticeable at first, but as they progress to advanced stages, the symptoms become severe.

If you notice any abnormalities, please visit a veterinary hospital as soon as possible.

Internal Organs and Digestive System Cancers

Symptoms such as loss of appetite, weight loss, vomiting, and diarrhea may appear. The main cancers include the following:

Additionally, if Hepatocellular Carcinoma or Liver Cancer or metastatic cancer from other organs affects the liver, it can result in diminished energy and appetite.

Incidentally, “approximately 90% of heart tumors in dogs are Hemangiosarcomas”, and Hemangiosarcoma can also develop in the spleen and liver. If these tumors grow large, they can rupture within the abdomen, leading to massive internal bleeding and potentially death.
When a dog develops a brain tumor, various symptoms can appear depending on the location of the cancer, such as “seizures,” “ataxia,” “loss of appetite,” “changes in taste,” and “vision impairment.”

Moreover, histiocytic sarcoma is an extremely malignant cancer that can lead to death within days of discovery.

It can metastasize to the liver, spleen, bone marrow, lymph nodes, brain, bones, joints, and throughout the entire body.

Osteosarcoma is a cancer that originates from bone cells called osteoblasts, and may cause symptoms such as abnormal gait and pain.

Bladder and Urinary Tract Cancer

There can be symptoms such as difficulty urinating or defecating, blood in the urine, and blood in the stool.

These are relevant.

Liver Cancer

In dogs, liver cancers can be either primary or metastatic, where other cancers spread to the liver. Primary liver cancers / liver tumors include:

The liver is known as the silent organ, making it difficult to detect cancer in its early stages.

However, in advanced or terminal stages of liver cancer, symptoms such as loss of appetite, lethargy, ascites, and jaundice may appear.

The 10 Causes of Cancer in Dogs

The primary causes of cancer in dogs include:

Decreased Immunity

Cancer and immunity in dogs are closely related.

It is unavoidable for errors (abnormalities) to occur in a dog’s cells due to various reasons.

Typically, even if abnormal cells occur in a dog’s body, the immune system detects, attacks, and eliminates these abnormal cells, preventing cancer from progressing.

However, if the immune system is compromised due to stress, aging, or other factors, it may fail to control the growth of the cancer, allowing it to grow visibly.

On the other hand, even if a dog has developed cancer, restoring immune function can help suppress the cancer.

Aging

Aging is a significant risk factor for cancer development in both dogs and humans.

One reason for the increased incidence of cancer in dogs is their longer average lifespan.

As dogs age, their immune system weakens, making it harder to detect, attack, and eliminate cancer cells, thereby increasing the likelihood of cancer.

It is recommended to incorporate immune support measures when your dog reaches middle to old age.

Genetics

Genetic factors are also a cause of cancer in dogs.
For example, some dogs are more prone to melanomas, and others to mammary gland tumors. Certain breeds are more susceptible to specific types of cancer.
However, in the case of cancer in dogs, acquired factors have a greater impact than congenital genetic factors. Therefore, please ensure to maintain a proper diet and living environment for them.

Chemicals

Chemicals, including pesticides, increase the incidence of cancer in dogs. Try to minimize the intake of such chemicals into their bodies.

Also, special attention is required when a cohabiting pet is undergoing anti-cancer drug treatment.

UV Rays & Radiation

It is believed that dogs exposed to strong UV rays or radiation are more likely to develop cancer.

It is advisable to avoid walking your dog during bright daylight and instead take them for walks in the early morning, evening, or night.

Tobacco Smoke (Secondhand Smoke)

While dogs do not smoke, they can develop cancer due to secondhand smoke if their family members smoke.

Tobacco smoke contains many carcinogens, so if you smoke, please make sure to do so away from your dog.

Chronic Inflammation

Chronic inflammation in dogs can stimulate cells and make it easier for cancer cells to develop.

Identify and eliminate the causes of inflammation, and give oils with anti-inflammatory effects like EPA and DHA appropriately to help reduce inflammation.

Hormones

Cancers such as mammary gland tumors (breast cancer) and prostate cancer are strongly influenced by hormones.

Neutering male dogs and spaying female dogs can prevent hormone-related diseases which often occur in middle-aged and older dogs, and statistically, it leads to longer lifespans.

Viruses

Chronic inflammation caused by viral infections, such as papillomavirus, can potentially lead to cancer in dogs.

Viruses can be eradicated if the immune system is functioning well, so always work to boost your dog’s immune system.

Obesity

Obesity in dogs can lead not only to cancer but also to various diseases like heart disease, arthritis, and diabetes.

A high carbohydrate intake can easily lead to obesity, so paying attention to their regular diet is crucial.

Five Cancer Treatments for Dogs

When a dog is diagnosed with cancer, it is common to undergo treatments such as “surgery and chemotherapy,” “steroids and antibiotics,” and in well-equipped hospitals, “radiation therapy.”

Surgery

The advantage of surgery is that it can simultaneously remove the cancer itself, the surrounding tissues, and any lymph nodes that have metastasized. This type of surgery to remove all cancer cells is called curative surgery.
### Surgery

Surgery is a treatment method that can potentially cure cancer if the cancer has not metastasized and remains localized (low invasiveness).

**Disadvantages of surgery for dogs include**:
– The necessity of general anesthesia,
– Significant physical stress due to the incision,
– The possibility of postoperative complications if the removed area results in loss of organ function.

Furthermore, if the cancer has spread, it becomes challenging to completely remove it through surgery.

### Radiation Therapy

Radiation therapy involves irradiating the cancer to destroy it.

Similar to surgery, radiation therapy is a local treatment that is effective when the cancer is localized. Unlike surgery, it is less painful because it does not involve incisions and makes it easier to preserve organ function. **It also has the advantage of being able to treat tumors located deep within the body or in the brain, where surgery might be difficult**.

However, **general anesthesia is required when a dog undergoes radiation therapy, which imposes some physical burden on the dog**.

**Disadvantages of radiation therapy include**:
– It is not suitable for metastatic cancer, similar to surgery,
– The need for general anesthesia,
– The potential for inflammation due to damage to healthy cells,
– Treatment availability is often limited to well-equipped hospitals like university hospitals,
– High costs associated with the treatment.

### Chemotherapy

The basic concept of chemotherapy is to kill cancer cells using strong toxins (chemotherapeutic agents).

**Advantages**:
– It can treat cancer that has metastasized,
– It can treat blood cancers,
– It does not require general anesthesia.

**Disadvantages**:
– Significant side effects,
– Potential bone marrow damage leading to decreased white blood cells and platelets, loss of appetite, vomiting, and overall decline in strength,
– Development of drug resistance limiting the effectiveness.

Some veterinarians may explain that “dogs are less prone to the side effects of chemotherapy,” but **dogs, just like humans, can experience side effects such as loss of appetite, fatigue, nausea, vomiting, diarrhea, and hair loss**.

Owners should carefully observe their dog during chemotherapy treatment and consult with their veterinarian if they notice any unusual behavior after treatment.

—

### Articles Related to Chemotherapy

### Treatment for Recurrence or Metastasis

Even if a dog undergoes surgery or radiation therapy to treat cancer, recurrence and metastasis are not uncommon.
Radiation therapy poses a challenge as the issue of exposure makes repeated treatments difficult. However, depending on the cancer’s state and overall health condition, another surgery may be considered.

If surgery or radiation therapy is not feasible, chemotherapy (including molecular targeted drugs like Palladia) might be suggested. Nonetheless, in many cases, the disadvantages (side effects) often outweigh the benefits (effects).

Aggressive treatment does not necessarily equate to treatment aimed at curing cancer. It is crucial to thoroughly discuss your beloved dog’s overall health, cancer condition, and the potential benefits and side effects of chemotherapy with your veterinarian before deciding whether or not to pursue chemotherapy.

Please note that not opting for chemotherapy does not equal neglect or lack of options. The following alternative therapies are approaches that can be started even if your dog has insufficient physical strength.

Alternative Therapies

While surgery, radiation therapy, and chemotherapy have their merits, they almost invariably lower immune system function and often diminish the Quality of Life (QOL).

Moreover, for advanced or terminal cancer cases where surgery is not an option, treatments that place a significant burden on the body can be challenging to perform.

However, many dogs maintain their QOL and sustain their vigor and appetite by incorporating dietary modifications and using supplements like Cordy. Therefore, even if your dog is diagnosed with advanced or terminal cancer and a limited prognosis, please don’t give up hope.

Combating Cancer by Utilizing Immunity

Our proposal aims to enhance both physical strength and immunity without burdening your dog, thereby fighting cancer.

While we cannot guarantee results, this method is low-risk and tends to offer significant benefits.

The recommended steps are as follows:

Regarding Diet

Since diet is an everyday activity, it plays a crucial role in cancer prevention and is extremely important after a cancer diagnosis.

Cancer heavily consumes glucose for its growth, which is the principle behind PET-CT scans.

Reduce Glucose Intake

By reducing the amount of carbohydrates and sugars in daily meals and snacks, the glucose supply essential for cancer’s growth can be lowered, potentially inhibiting the cancer’s progression.

Rice, bread, noodles, and sweets are particularly high in carbohydrates, as are ingredients like potatoes and pumpkins. It is advisable to minimize their intake.
※ Note that even mixed grain rice contains high levels of carbohydrates, so caution is necessary.

While changing your dog’s diet alone may not cure cancer, it is crucial to implementing a certain degree of control to prevent cancer from growing uncontrollably.

We highly recommend checking the food labels (nutritional information) once again.
Since pet food is not required to display carbohydrate content, it is recommended to choose food with high protein content.

It’s advisable to select food with at least 30%, preferably 35%, protein per 100 grams.

Proactively Intake Essential Fatty Acids

Essential fatty acids are vital oils necessary for a dog’s survival.

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are examples of these essential fatty acids.

These oils are crucial for cancer treatment involving inflammation, as they are expected to work on reducing inflammation.

We recommend blue fish like mackerel, saury, sardines, and mackerel, as well as salmon oil and Krill Oil.

Details About Dietary Therapy

Revising the diet is also important for improving cancer symptoms.

A low-carb, high-protein diet is highly recommended to help curb the progression of cancer.

We have compiled articles about dietary therapy for your reference, so please take a look.

Proactively Addressing Immunity

Starting chemotherapy treatment will almost certainly lower physical strength and immunity.

If your dog’s physical strength and immunity decline, their quality of life (QOL) will drop. Even if treatment prolongs life slightly, it might only extend the time they suffer from cancer.

Therefore, to maintain physical strength and immunity, start with providing a good diet to build strength so they won’t have to abandon treatment due to side effects.

Make sure not to let their immunity decline.

Originally, immunity is the main agent in suppressing cancer, and chemotherapy acts merely as an aid.

By proactively utilizing alternative therapies, dietary therapy, and Cordyceps, we aim to improve prognoses through immunity measures.

We believe in harnessing the best aspects of various treatments. Relying solely on chemotherapy is clearly insufficient.

It is essential to combine complementary treatments.

For a Treatment Free of Regret

We have compiled information that pet owners whose dogs have been diagnosed with cancer should know first and foremost.

The content here is based on knowledge and ideas gathered from exchanges with advanced veterinarians and pet owners.

We never impose our views.

It’s natural for there to be a variety of perspectives and decisions.
We don’t want the owners to have any regrets. We don’t want you to regret your choices later on.

Should you proceed with treatment or not?

Surgery or chemotherapy?

There is no correct answer to these questions when it comes to cancer treatment.

Conversely, we can say this:

Any choice made by the owner out of love for their dog is the right choice.

We want you to understand the realities of cancer treatment to help you make better choices.

You don’t need to memorize every detail or test result.

However, we want you to know that there are many things you can do at home and as a family, without relying solely on surgery, chemotherapy, or leaving everything to the veterinarian.

Cordy, which has potential immunomodulatory functions, may help suppress tumor growth and prevent recurrence.

While it is uncertain how much response or improvement can be expected, there is a significant possibility that at the very least, your pet will regain appetite and energy.

When using medications like chemotherapy, steroids, or antibiotics, liver function decline is a concern.
In such cases, using domestically produced SPF-derived porcine placenta powder in conjunction may help minimize liver damage.
Even in cases where liver values have already worsened, domestically-produced SPF-derived porcine placenta powder can improve liver function within about a month in many instances.

Furthermore, since tumors, cancer, and sarcomas often involve severe inflammation, it seems effective to give Krill Oil extracted from Antarctic shrimp containing EPA/DHA, which has expected anti-inflammatory effects.

Our lab continues research on Cordy, which has expected immunomodulatory effects, domestically-produced SPF-derived porcine placenta powder, which is expected to protect liver function, and Krill Oil, which is expected to have anti-inflammatory effects. If you have any questions, please feel free to contact us.

There are also many case studies and improvement examples available for you to see.

Feel free to consult us at any time.

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

Melanoma is a malignant tumor that can develop in the oral cavity or on the skin of cats. Melanoma is extremely malignant and progresses rapidly, often leading to recurrence even after surgery. However, it is believed that immune system interventions can improve the cat’s condition, maintain their quality of life (QOL), and restore their energy and appetite. In fact, there have been numerous cases where cancer in cats was controlled by implementing immune strategies using Cordy. This page summarizes the causes, symptoms, treatments, and tips for improvement and cure of melanoma, along with numerous improvement examples. We hope to be a source of support and a light of hope for everyone.

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

If Your Cat Is Diagnosed with Melanoma (Skin Cancer)

In addition to melanoma, cancers that can develop on the skin include squamous cell carcinoma and mast cell tumors.

When a cat is diagnosed with melanoma or skin cancer, treatments such as surgery, chemotherapy, and radiation may be considered.

Because these cancers are aggressive, they can often recur shortly after treatment or may not respond effectively, despite the rigorous treatment that puts a significant burden on the cat.

However, it is believed that even if a cat has melanoma, the prognosis can be significantly improved, and QOL can be maintained to restore energy and appetite depending on the approach taken. There have indeed been cases where melanoma has been controlled.

Overview of Feline Melanoma (Skin Cancer)

Melanoma, which frequently occurs in cats, is a type of skin cancer also known as malignant melanoma.

It progresses rapidly, tends to recur, easily metastasizes to the lungs, and is considered one of the most aggressive types of cancer.

While the incidence in humans is a few per 100,000 people, it is slightly higher in cats, particularly those with black fur.

In the oral cavity, possible irritants include hard dry food, bone chews, and chewing toys.

If it appears near the paw pads, it could be due to the impact from a strenuous walking route, or the hot asphalt in midsummer might be major contributing factors.

For humans, the cause is considered to be ultraviolet rays from the sun.

Short-haired breeds might face a slightly higher risk.

Of course, the most significant cause is not these external factors.

It is an internal issue, specifically a decline in immune function (disorder of the immune system).

When the immune system does not function properly, it cannot suppress the occurrence and growth of melanoma.

I will explain immune strategies later.

First, let’s discuss what melanoma is and the general treatment options.

Characteristics of Melanoma in Cats

Both types of tumors originate from melanocytes, which produce melanin pigments.

They are characterized by being darker than the surrounding area.

If they are larger than a mole, elevated, or have unclear boundaries, caution is required.

Particularly if it grows rapidly after onset, it should be examined by an experienced veterinarian.

Melanomas mostly occur in skin areas exposed to the external environment, such as the oral cavity and paws, and rarely originate from internal organs.

When found in the lungs, it is almost always due to metastasis from another site.

In cats, melanoma is often found inside the eyeball.

Generally speaking, melanoma is known for its rapid progression, which is true due to the large number of “cancer stem cells” thought to be involved in the rapid progression of melanoma.

For more information on cancer stem cells, considered the orchestrator of cancer, please refer to Suppressing Cancer Stem Cells to Overcome Pet Cancer.

Stimulating melanomas can speed up their growth, so avoid poking with sharp objects or handling them roughly.

Even examinations can be a form of stimulation; thus, it is best to avoid excessive testing.

Melanoma is a type of cancer that easily metastasizes to the lungs. In advanced melanomas, lung metastasis is often detected.

If lung metastasis is found, complete cure through conventional treatment alone becomes very challenging. It becomes important to build a treatment plan aiming for coexistence with melanoma.

Symptoms and Early Detection Methods

Due to the lack of obvious symptoms, detecting melanoma through changes in the pet’s condition is challenging.

Routine checks inside the mouth and on the soles of the feet are important for early detection. These areas are common sites where melanomas tend to occur, especially in dogs.

Engage regularly in physical interaction with your pet, inspecting inside their mouth, eyes, and the soles of their feet. If you notice any abnormalities, it is recommended to consult a veterinarian as soon as possible.

Many melanomas appear in locations that are visible to the naked eye.

Since melanomas are often darker in color compared to surrounding areas, this can serve as a clue for detection.

They are frequently mistaken for moles or spots, so check the following characteristics for proper differentiation.

Melanomas are often discovered during regular check-ups or daily examinations. It is advisable to choose experienced veterinarians or groomers to increase the chances of early detection.

Melanoma Examination Methods

As with other skin cancers, the veterinarian first observes with the naked eye. If there is suspicion, a part or the entirety of the tumor is taken for examination.

The testing company will report the level of suspicion for melanoma.

Lung Metastasis Tests – Examination of Cat Melanoma

To check for lung metastasis, an X-ray examination is conducted. If there is a tumor about 1 cm, it will appear on the X-ray image.

CT scans may detect even smaller tumors that are not visible on X-rays.

However!

Even if a shadow appears in a CT scan, it does not confirm melanoma by itself.
Furthermore, even if melanoma is found, treatment can often be challenging.

CT scans involve much higher radiation exposure than X-rays and pose risks associated with general anesthesia, putting stress on the cat.

Therefore, if you are advised to undergo a CT examination, it is recommended to consult with your veterinarian about whether the benefits outweigh the risks.

The main advantage of a CT scan is determining if pursuing treatment would be meaningful.

If lung metastasis is present, procedures like eye removal, jaw amputation, or limb amputation would not lead to a cure, thus making those treatments unnecessary.

CT scans can also provide a more accurate prognosis regarding the cat’s remaining lifespan compared to X-ray examinations.

Incidentally, the cost of a CT scan is generally much higher than that of an X-ray examination.

Ultrasonography (ultrasound diagnostic imaging) is another method to examine the inside of the body.

While ultrasound can check for lymph node metastasis outside the lungs, it is nearly incapable of detecting metastasis in the lungs. This is because lungs filled with air are the most challenging area for ultrasound to examine.

Common Treatments for Cat Melanoma

The most effective treatment is surgical intervention.
The efficacy of chemotherapy against melanoma is not very high.

Radiation therapy, which is conducted in some facilities, may also not be very helpful.

All treatments carry considerable risks.
It is recommended to consider both the benefits and risks carefully before selecting a treatment method.

Curative Surgery

Curative surgery essentially aims for complete recovery.

To minimize the risk of recurrence, the tumor and the surrounding area are excised as extensively as possible.
Naturally, there are limits to how extensively a tumor can be excised, leading to specific types of surgeries as follows:

You might question whether such extensive excision is necessary, but the invasive nature of melanoma is incredibly high.

Even with such measures, there are often cases where a small number of cancer cells remain, leading to recurrence despite undergoing a radical surgery.

There is no doubt that radical surgery significantly reduces the number of cancer cells.

Therefore, even if recurrence occurs, the time until recurrence can be significantly extended. It is possible that melanoma will not recur at all during the pet’s lifetime.

If postoperative immune strategies are thoroughly implemented to halt the cancer’s progression, there is also the potential to spend the rest of the pet’s life without recurrence.

A point to note is that anesthesia during surgery greatly reduces immune function.

By rapidly restoring immune strength post-surgery and realigning the compromised immune system, the risks of melanoma recurrence and metastasis can be greatly minimized.

By administering Cordy, you may support the immune system to help reduce the risk of melanoma recurrence and metastasis.

While radical surgery has its benefits, it also has the following drawbacks, which means not all pet owners choose this option.

It’s important to receive thorough explanations from your veterinarian to decide whether the surgery is suitable for your pet.

Palliative Surgery

Palliative surgery is also known as debulking surgery, where only part of the tumor is removed.

Since it is surgery with the premise of leaving cancer cells behind, it cannot achieve complete cure through surgery alone.
The aim is to temporarily resolve issues caused by the tumor.

For example, the following symptoms may be alleviated through palliative surgery:

Many might not have a positive image of the term palliative, but palliative surgery is a proactive procedure aimed at improving QOL, helping both the owner and their beloved dog enjoy better times together.

Tooth extraction can also be considered a type of palliative surgery. Tooth extraction might significantly slow the progression of oral melanoma.

Melanoma Treatment for Cats: Chemotherapy

To be frank, chemotherapy is not expected to be very effective against melanoma.

As mentioned before, melanoma is a type of cancer with many “cancer stem cells.” Cancer stem cells exhibit strong resistance to chemotherapy.

Even if there is some response, the disadvantages (side effects) caused by chemotherapy often outweigh the benefits in most cases.

I have even received reports of dogs in good health passing away a few days after chemotherapy was administered.

To avoid such situations,

• Ensure there are no risks associated with the proposed chemotherapy treatment,
• Confirm that the treatment will not cause adverse effects due to side effects,
• Ensure that the treatment will not hasten the end of life.

It is recommended to thoroughly check for these potential disadvantages.

If the pet is anemic, has low albumin levels, or has decreased liver or kidney function, side effects are more likely to be severe, increasing the risk.
In such cases, a more cautious approach is desirable.

If your veterinarian recommends chemotherapy, please take the time to read articles summarizing the side effects of chemotherapy.

Treatment of Melanoma in Cats: Radiation Therapy

When melanoma has progressed to areas that are difficult to operate on, radiation therapy may be suggested.

For example, if oral melanoma has extensively infiltrated areas near the eyes, surgery with adequate margins is not possible. In such cases, radiation therapy is still an option.

However, since it is difficult to completely eliminate cancer cells with radiation therapy, it is not considered a curative treatment.

Additionally, it can damage normal tissues, often resulting in aftereffects.

In the case of oral melanoma, radiation targeting the eye can cause dry eye (reduced tear production), vision impairment, or blindness.

Cats cannot verbally communicate, making it challenging to understand, but dry mouth (reduced saliva production), altered taste, and altered smell are not uncommon.

In human radiation therapy, treatment is administered gradually over several days.
In contrast, cats receive intense radiation in just a few sessions, making aftereffects more likely.

Due to these and other reasons, careful consideration is necessary when opting for radiation therapy.

Alternative Therapy (Natural Therapy) for Melanoma in Cats

As the name suggests, alternative therapy refers to treatments that substitute conventional therapies.

Various treatments have been devised and are being carried out in some advanced animal hospitals.

Many alternative therapies have a lighter burden on the body, allowing for the possibility of combining several treatments simultaneously.

The low level of damage means that these therapies are less dependent on the stage or condition of the disease. Alternative therapies can be implemented before surgery, to prevent recurrence after surgery, and in cases where surgery is not possible or where there are pulmonary metastases.

We strongly recommend considering alternative therapies in the following situations:

Dietary Therapy

The goals are to slow down the growth of cancer, build strength, and improve anemia and albumin levels.

Our company and some animal hospitals place a significant emphasis on nutritional approaches as the foundation of treatment.

The primary energy source for cancer is carbohydrates. A diet therapy that limits carbohydrates as much as possible carries considerable significance from a scientific perspective.

With virtually no disadvantages, it’s worth trying.

If your pet can accept this without stress, give it a try. If it seems too stressful, consider implementing just part of it.

You may overcome this with some adjustments in the seasoning methods or the temperature of the food.

While this dietary therapy requires more effort compared to the convenience of dry food, it is not fundamentally difficult.
Please consider it as a part of the treatment and spend a little time on it. It won’t be a waste.

To help reduce the hassle even a little, we have collaborated with animal hospitals to create a list of ingredients. Please take a look.

Pets and the Principle of Dietary Therapy – Ingredients to Fight Cancer

Eliminating the Causes Worsening Melanoma in Cats

The cause of melanoma is believed to be chronic irritation.

Any treatment will decrease in effectiveness unless this is removed. Below, I present the causes and countermeasures for melanoma for your reference.

Reducing Irritation to the Soles of the Feet

Try to avoid paved roads as much as possible and choose walking routes with soft soil or grass to reduce irritation. Walking on hot surfaces should be strictly avoided.

Not only heat stimuli but also chemical irritants from asphalt can be a concern, although ideal walking routes are not available everywhere. How about having them wear shoes only during walks?

Reducing Oral Irritation

If there is melanoma in the oral cavity, it is safer to avoid dry, hard food. The tumor might enlarge due to irritation.

One way is to soak the food in warm water or switch to semi-moist types, but consider switching to human-grade food if possible.

Various chemicals included in pet food might also affect the worsening of melanoma.

These chemicals are added to prevent dog food from rotting, molding, or becoming infested with pests. They might include substances that are not allowed in human food or might be present in volumes exceeding human standards.

Treatment for Periodontal Disease

Inflammation from periodontal disease might also act as chronic irritation. If you have any teeth that are already loose, it is advisable to have the veterinarian extract them.

If a tooth falls out when no one is around, there is a risk of severe bleeding.

Regular oral care should be conducted to counter periodontal disease. I understand that many pets dislike brushing, but toothbrush gloves are great because they allow you to make tooth brushing an enjoyable bonding time.

Why not give them a try?

Reviewing Medication

All medications have a poisonous aspect.

Some pets are on long-term antibiotic use. Antibiotics can kill both good and bad bacteria, disturbing the normal bacterial balance in the oral cavity.

This imbalance not only affects the oral cavity but also the gut, leading to reduced immunity. Long-term steroid use can also compromise the immune system.

By gradually reducing antibiotics, steroids, and other medications, you can restore immune function.

Be aware that sudden discontinuation of steroids can lead to health deterioration, so they should be tapered off slowly. Always communicate any attempts to reduce medication with your veterinarian.

Reducing Stress

Strong stress is a clear factor that lowers immunity. Since immunity is crucial for cancer suppression, stress management is essential.

If there are incompatible housemates, separate them. If there is noise from construction around, move them to a quiet room.

Also, stress from the owner can affect your cat. The owner’s sad expressions can be stressful for the cat. Engaging with them with a smile is also an essential part of treatment. Please hang in there.

Please ensure that the measures introduced on this page do not cause stress to your cat. Sometimes it’s better to proceed slowly and help them get used to changes gradually.

Boosting Immunity with Cordy

When your beloved cat has melanoma, boosting immunity can improve their QOL (quality of life).

There are many consultations from people whose cats had a recurrence after surgery, whose cats underwent ineffective chemotherapy and the disease progressed, or who were told nothing could be done.

Generally, melanoma is considered highly malignant and progresses rapidly, leading to poor prognosis.
However, we believe that by properly boosting the immune system, we can help your dog regain its appetite and vitality, allowing it to live its life to the fullest.

If the current treatment is not working well, seems too taxing on your pet’s body, or even if the treatment is going well but you still want to improve your pet’s quality of life (QOL), we recommend considering the use of Cordy.

There have been multiple reports of long-term survival and improvement in dogs with melanoma that were given Cordy.

If you have any questions, please feel free to contact us.

In Conclusion

Melanoma is one of the most aggressive types of cancer.

While curing any cancer is challenging, melanoma is especially difficult to treat successfully.

Standard Western treatments are applied in the treatment of melanoma, but they have not yielded very good results.

It is not uncommon to find dogs that have undergone major surgery only to experience recurrence or lung metastasis.

Western treatment methods often center around the concept of thoroughly attacking cancer cells by excising them or killing them with strong toxins.

These treatments might reduce the tumor size, but they tend to overlook the overall condition of the dog’s body and the underlying causes of the cancer.

To avoid the “can’t see the forest for the trees” situation and to ensure that the priority given to treatment does not result in irreversible damage, please be cautious.

The primary goal of treatment should be to maintain your pet’s QOL and to increase the enjoyable time you spend together.

It is crucial to consider whether the treatment is worth the sacrifices made.

Most pet owners find it challenging to be satisfied with a situation where their dog loses its eyes, jaw, or limbs and becomes weakened by chemotherapy that was hoped to be beneficial.

Please be careful not to fall into the common pattern of “the tumor got smaller, but so did the flame of life.”

Even if your pet falls ill, do not simply leave everything to the veterinarian. Think together as a family about how to ensure a good time for your pet.

There are things owners can do for their pets that are not outlined on this page. If you are interested in trying something yourself, please reach out to us. We will support you as best we can.

When your pet is diagnosed with melanoma, it is crucial to focus on immune measures regardless of whether you choose to pursue treatment.

Our laboratory continues to research whether administering Cordy during periods of weakened immunity can expedite the recovery of the immune system.

We cannot predict the extent or likelihood of improvement, but at the very least, there is a significant possibility that your pet can regain its appetite and vitality.

If you are using medications such as anti-cancer drugs, steroids, or antibiotics, there are also concerns about liver function deterioration.
In such cases, combining with Placental extract powder from domestically-produced SPF pigs may help minimize liver damage.

Even in pets with already deteriorated liver values, there are numerous cases where liver function improved within about a month after using the placental extract powder from domestically-produced SPF pigs.

Moreover, since melanoma often involves inflammation, providing EPA/DHA Krill Oil extracted from Antarctic Krill, which has anti-inflammatory properties, might be effective as well.

Our laboratory continues to research Cordy for its expected immune-modulating effects, the liver-protective effects of the placental extract powder from domestically-produced SPF pigs, and the anti-inflammatory effects of Krill Oil. If you have any questions, please contact us.

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

• Feline AIDS, once it develops, has no cure and leads to immune deficiency, making it a challenging disease.
• The virus FIV, which causes feline AIDS, infects the immune cells of cats but does not show significant symptoms in the early stages.
• Through efforts to boost the immune system, it is possible to improve the cat’s condition, maintain its quality of life (QOL), and restore its appetite.

What is Feline AIDS?

Because no fundamental cure has been found for this disease, once it develops, there is no cure, and it leads to immune deficiency, making it a difficult disease.

However, infection does not mean that severe symptoms will appear early on; there is a latent period of about five years (this can vary among individuals).

During this time, the cat can live normally, just like a healthy cat.

Because the latent period is long, some cats can live out their natural lives without developing symptoms.

Therefore, finding out that a cat is infected is not a reason to be overly pessimistic.

However, the long latent period means there is a possibility of unknowingly infecting other cats.

If it is confirmed that a cat is infected, it is an important courtesy to keep the cat indoors strictly.

Causes of Feline AIDS Infection

The FIV virus itself is very weak, so it does not spread through the air.

It is said that about 10% to 20% of cats are infected with feline AIDS, so outdoor cats that frequently interact, mate, or fight with other cats have a higher risk of contracting the virus.
※Feline Immunodeficiency Virus (FIV) and Human Immunodeficiency Virus (HIV) are different viruses. Rest assured, even if you are bitten by a cat infected with feline AIDS, you will not develop AIDS.

Effective Prevention of Feline AIDS

Once feline AIDS develops, there is no cure. However, by having your cat neutered or spayed while they are still young and not at risk of infection, you can reduce the risk of infection to almost 0%.

Neutered cats are less likely to engage in mating and fighting, significantly reducing the risk of infection.

About the Feline AIDS Vaccine

However, even if vaccinated, allowing close contact with other cats will not prevent infection.

Please consider the vaccine as merely supplementary. Note that there is no effect if the vaccine is administered after infection.

If your cat’s physical or immune health is compromised, vaccinating might worsen their condition. Please consider your cat’s health status when thinking of administering the feline AIDS vaccine.

Methods to Suppress the Onset of Feline AIDS

Feline Immunodeficiency Virus (FIV) is not a particularly strong virus.

If the cat is healthy with a strong immune system, it can suppress the proliferation of the virus.

However, if the cat’s immune system weakens, the virus can multiply, leading to the onset of feline AIDS.

Once feline AIDS has developed, it becomes challenging to control the progression of the disease.

If a positive test result is received, listen to the veterinarian’s advice to prevent the disease from developing.

It has been reported that a clean environment can delay the onset of the disease.
Ensure indoor living to definitively prevent the infection from spreading to other cats.

Symptoms of Feline AIDS

The virus that causes feline AIDS, FIV, infects the immune cells of cats. In the early stages of FIV infection, there are no particularly noticeable symptoms.

As FIV starts to proliferate, the immune system weakens progressively.

Consequently, even bacteria or fungi that pose no threat to healthy cats can cause diseases.

This is known as opportunistic infection.

The fatality is not directly caused by feline AIDS itself but by various infections due to the weakened immune system.

Opportunistic Infections – Main Symptoms of Feline AIDS

The body can succumb to minor bacteria or viruses, such as those causing intestinal flora imbalances or colds, which are otherwise harmless to a healthy body.

Anemia and Bleeding – Main Symptoms of Feline AIDS

The Feline Immunodeficiency Virus (FIV) destroys the bone marrow responsible for hematopoietic functions, making it impossible to produce new red blood cells, resulting in anemia.

Similarly, the production of platelets is halted, making it difficult to stop bleeding.

Tumors (Cancer) – Main Symptoms of Feline AIDS

Both humans and cats have cancer cells forming in their bodies daily, but the immune system suppresses their proliferation.

However, with immune suppression, the body can no longer control the growth of cancer cells, leading to cancer development.

Stages of Feline AIDS

Based on clinical symptoms and the course of infection, feline AIDS is classified into the following five stages:

Acute Phase

Following infection with the virus, symptoms such as fever, diarrhea, anemia, leukopenia, thrombocytopenia, and lymph node enlargement appear.

The acute phase lasts from several weeks to about four months after infection.

During this period, antibody tests (anti-FIV antibodies) will become positive.

Asymptomatic Carrier Phase

This phase occurs when the symptoms of the acute phase disappear. It is a latent period where, even if infected with FIV, the cat does not show immediate symptoms.

The asymptomatic latent period can last from several months to several years, depending on the cat’s health and immune status. Some cats may never show symptoms despite being infected with FIP.

There are no noticeable symptoms, but antibodies and the virus are still present.

Persistent Generalized Lymphadenopathy Phase

Symptoms such as swelling of lymph nodes throughout the body, where immune cells are concentrated, are observed. This period is short, lasting only 2 to 4 months, and is often overlooked.

AIDS-Related Complex (ARC) Phase

As feline AIDS manifests and the cat’s immune system weakens, the body becomes more susceptible to bacterial and viral infections, leading to various symptoms such as stomatitis, respiratory, gastrointestinal, and skin diseases.

Acquired Immunodeficiency Syndrome (AIDS) Phase

In the final stage, the immune system is completely lost, leading to various symptoms such as anemia, malignant tumors, and opportunistic infections, eventually resulting in death.

Due to the lack of immune function, chronic conditions like stomatitis, respiratory infections, and skin and ear infections are also observed.

Treatment for Feline AIDS

For the infection, interferons and antibiotics (for bacteria) are mainly used.

Boosting Immunity

Enhance your cat’s immunity to prevent infections.

Moderate exercise and high-quality food can be beneficial.

When concerned, consider using Cordy to maintain immune strength.

It is crucial to prevent the onset of symptoms even if infected with the feline AIDS virus.

If symptoms do appear, focus on maintaining immunity to prevent disease progression.

Feline AIDS Prevention

When a cat is infected with the AIDS virus (FIV) and develops feline AIDS, it eventually leads to immune deficiency and death, leaving owners feeling hopeless.

Indeed, while there is no current cure for a cat that has developed AIDS, maintaining immunity with Cordy to prevent immune deficiency can help slow disease progression.
As a measure to support liver function, we recommend giving Placenta Extract from Domestic SPF Pigs, and for anti-inflammatory measures, Krill Oil, which is rich in EPA/DHA. Additionally, to supplement essential nutrients (especially to prevent albumin deficiency), provide amino acid supplements such as BCAA and Green Tripe. These measures may help maintain overall vitality.

If you have any questions, please feel free to contact us.

* We are also researching the application of specific Cordyceps species with potential immune-modulating functions for humans.

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

Improving Kidney Failure and Kidney Disease

Many older cats, in particular, exhibit a decline in kidney function or have kidneys that are not working properly.

Damaged kidneys cannot be restored.

Therefore, to prevent the progression of kidney failure symptoms, it is crucial to maintain the function of the remaining kidneys and reduce the load on the kidneys.

By administering drips (intravenous or subcutaneous) to promote the excretion of toxins, we aim to alleviate symptoms and improve kidney function.

In pre-renal or post-renal cases, it is also important to treat the underlying diseases causing the condition.

To slow the progression of kidney failure, alongside treatment at animal hospitals, it is essential to take care of the kidneys and maintain physical strength and kidney function.

Here are some recommended methods that can be done at home.

If your pet’s vitality and appetite begin to recover, it means your efforts are paying off.

For any questions or concerns regarding the use of Cordy, EPA/DHA, or BCAA/green tripe, please feel free to contact us.

Click here for inquiries

Kidney Failure and Kidney Disease in Dogs and Cats

This disease can occur in both dogs and cats, but it is more common in cats. Reports from overseas state that 30% of cats over 15 years old suffer from chronic kidney failure.

One suggested reason for the higher incidence of kidney failure in cats is their low water intake, which places a burden on the kidneys to produce concentrated urine, making them more prone to kidney disease as they age.

Additionally, a 2016 study suggested that a special protein called “AIM” might not be functioning adequately in cats’ kidneys, which could be a factor in chronic kidney disease.

In both humans and animals, the kidneys act like a coffee filter. They filter and remove waste products and salts while reabsorbing necessary substances to produce urine, which helps regulate body fluids. When this function is compromised, waste products build up in the body, causing various symptoms.

The failure to effectively expel waste products and toxins can lead to conditions such as ‘Uremia‘ or ‘Hyperkalemia‘.
The kidney, like the liver, is often referred to as a “silent organ,” and it is believed that by the time abnormalities appear in a blood test, more than 70% of kidney function has already been lost.

Whether in humans, dogs, or cats, once the kidneys stop functioning properly (become damaged), they cannot recover. Therefore, managing the damage to the cells of the kidneys that are still functioning is critical in coping with renal failure.

Although managing renal failure is challenging, dietary therapy and treatments can reduce the burden on the kidneys, allowing for a more peaceful remaining life.

Types of Renal Failure

Renal failure can be classified into three types depending on the location of the damage.

Renal failure can also be classified into two types based on progression: acute and chronic.

① Acute Renal Failure
As the name suggests, this type of renal failure occurs suddenly. It is often caused by urinary obstructions due to stones or by drugs/toxins.
It is a terrifying disease that can rapidly worsen in just one day.

② Chronic Renal Failure
Chronic renal failure occurs due to the gradual dysfunction of the kidneys’ filtration capacity.
It progresses over several months to years, and by the time symptoms become noticeable, more than 70% of the kidney’s function may already be impaired.
It is said that one in three cats and one in ten dogs will develop chronic kidney disease during their lifetime, making it one of the leading causes of death, especially in cats.

Symptoms of Renal Failure

In acute cases, you may observe symptoms such as loss of appetite, vomiting, diarrhea, and lethargy.
Some pets may exhibit signs of pain in their kidneys, leading to increased vocalizations or aggression.

In chronic cases, due to the gradual progression, noticeable symptoms may not always be present, but generally, increased water intake and increased urination are observed.

Other symptoms may include characteristic bad breath (ammonia odor) and anemia (due to decreased production of erythropoietin, which stimulates red blood cell production), as well as constipation due to dehydration.

If renal failure progresses and uremia develops, it can lead to neurological symptoms such as seizures and coma.

Diagnosis

Blood tests may show elevated levels of BUN (blood urea nitrogen), creatinine (Cre), and phosphorus (IP), along with low red blood cell counts.
(Abnormal values may also be seen in other parameters)

Urinalysis involving urine specific gravity, UPC (urine protein/creatinine ratio), and UAC (urine albumin/creatinine ratio) values can help diagnose renal failure.

Renal failure is categorized using the ‘IRIS staging system,’ which helps determine the extent of remaining kidney function based on the stage.

IRIS Stages
Stage	Cre (Creatinine)	BUN (Blood Urea Nitrogen)	Remaining Renal Function
Stage 1	Below 1.4 in dogs Below 1.6 in cats	No abnormality	33–100%
Stage 2	1.4–2.0 in dogs 1.6–2.8 in cats	Mild elevation	25–33%
Stage 3	2.0–5.0 in dogs 2.9–5.0 in cats	Moderate elevation	10–25%
Stage 4	Above 5 in both dogs and cats	Severe elevation	Less than 10%

Additionally, since 2015, Idexx (Idexx) has introduced the ‘SDMA’ test, which can detect chronic renal failure at an early stage, so it is recommended to include this test as well.
Other diagnostic methods may include X-rays, ultrasound, contrast imaging, and blood pressure measurement.

Treatment Methods

Treatment Methods: Reducing damage to the kidneys is crucial.

Typically, intravenous or subcutaneous fluids are administered to promote the excretion of toxins, aiming to alleviate symptoms and improve renal function.

In cases of prerenal or postrenal conditions, it is also important to treat the underlying diseases causing these conditions. In cases of acute renal failure, rapid deterioration of symptoms can lead to death, so prompt treatment is essential.

If treatment is delayed or the kidney damage is extensive, it may progress to chronic renal failure.

For chronic renal failure, in addition to fluid therapy, measures such as dietary changes, oral medications, and injectable medications can be used to slow the decline in renal function and prevent the worsening of symptoms.

※ When administering subcutaneous fluids, excessive fluid administration can put unnecessary strain on the body of dogs and cats.

Generally, subcutaneous fluids are absorbed within half a day to a day, but if absorption does not occur, the excess fluid may appear as edema.

Edematous areas tend to get cold easily, which can impede circulation, making waste excretion less efficient, and leading to decreased metabolism and lowered immunity.

Since subcutaneous fluids are often administered between the shoulder blades, edema is more likely to occur in the front legs, which can result in abnormal walking or paw shaking behaviors.

Rapid breathing or open-mouthed breathing may also occur.

The day after administering subcutaneous fluids, please check at home to ensure the fluid has been properly absorbed. If it has not been absorbed, adjust the amount of subcutaneous fluids accordingly.

Pitfalls of Kidney Prescription Diet

When kidney values exceed the normal range, a switch to a prescription diet is generally recommended.

The idea behind prescription diets is to reduce the burden on the kidneys by minimizing waste products, so these diets typically contain low amounts of protein.

However, considering that dogs and cats are naturally carnivorous animals (especially cats, which are obligate carnivores), excessive restriction of protein may lead to an energy deficit, resulting in improved kidney values but a lack of physical strength and vitality in many pets.

In fact, there is no clear evidence that protein restriction can prevent the progression of kidney disease in cats.

Important Aspects of Diet for Renal Failure

1. Ensuring adequate fluid intake
2. Using appropriate amounts of protein
3. Using high-quality protein (with an amino acid score close to 100)
4. Increasing fats

Fluid Intake

Consider switching from dry food to wet food or preparing homemade meals with plenty of soup.

Appropriate Protein

Since each individual has different capacities for processing protein, try using foods with slightly lower protein content than what you are currently feeding.

Regular blood tests can help monitor changes in kidney values and help determine the optimal protein amount for your pet.

High-Quality Protein

The amino acid score is an indicator of protein quality—the closer to 100, the fewer waste products generated during protein breakdown, which reduces the burden on the kidneys.

However, high-scoring amino acid foods (meat, fish, eggs) are also high in protein, so start with small amounts.

For pets with decreased kidney function, administering essential amino acids like BCAA can help improve symptoms.
Also, green tripe is recommended.

Increasing Fats

Reducing protein intake can lead to an overall energy (calorie) deficit.

If there’s an energy deficiency, the body’s proteins (such as muscles) will be used, resulting in an increase in waste products.

To prevent this, energy must be supplemented with carbohydrates and fats. However, both dogs and cats are not very efficient at digesting carbohydrates.

Especially in cats, many have grain intolerances and excel at metabolizing fats more than carbohydrates.

There are various types of fats, but in cases of renal failure where inflammation may be present in the kidneys, omega-3 fatty acids are recommended to reduce inflammation.

Sources of omega-3 fatty acids include plant-based oils like flaxseed oil and perilla oil, as well as animal-based EPA and DHA.

Plant-based omega-3 fatty acids are converted in the body into animal-based omega-3 fatty acids, which exhibit anti-inflammatory and anti-tumor effects. However, some dogs and cats may not efficiently carry out this conversion.

To ensure the desired effects, it’s recommended to directly provide EPA and DHA in the form of krill oil (EPA/DHA from Antarctic krill).

※ Excessive fat intake can strain the pancreas and potentially cause pancreatitis, so start with small amounts.

Furthermore, using Cordyceps to support kidney function and boost the immune system is also crucial.

Knowledge on Diets Beneficial for Kidney Function Recovery

• About Low-Protein Diets for Cats with Kidney Disease
• BCAA Supplementation for Dogs and Cats with Decreased Stamina and Poor Liver or Kidney Function
• Krill Oil for Anti-inflammatory Effects and Dementia Prevention

Prevention Methods

It is also important to supplement BCAAs for dogs and cats with decreased stamina and poor liver or kidney function.
Paying attention to the diet of dogs and cats on a daily basis can help prevent various diseases.
You can check the list of articles related to diet that you should pay attention to on a daily basis here.

>>Check Articles Related to Diet

To prevent kidney failure, it is essential to ensure proper blood flow to the kidneys and eliminate waste products. A key way to achieve this is by ensuring adequate water intake.

Unlike us, it is challenging to encourage dogs and cats to drink water proactively. Especially for cats, whose ancestors lived in deserts, their water intake tends to be lower compared to dogs.

Additionally, many pets are currently fed dry food, which means that their water intake from diet is virtually zero.

Increasing Water Intake can be achieved by soaking dry food or switching to wet food. Additionally, you can try placing multiple water bowls around, changing the water temperature, or using different types of bowls.

Moreover, simply increasing the amount of water intake is not meaningful without ensuring the pet properly urinates to expel waste products.

Some dry foods contain high levels of salt to enhance palatability for dogs and cats.
Particularly, lower-quality products tend to have higher salt content, and such foods generally contain a lot of additives like flavorings.

Limiting high-salt foods can reduce the burden on the kidneys, so it is also recommended to avoid treats, jerky, dried bonito flakes, and dried sardines.

When using commercial pet food, please be sure to check the ingredients and nutritional information thoroughly before purchasing. For early detection, especially once your pet reaches senior age, conduct regular blood and urine tests.

Additionally, in the case of cats, they may avoid using a dirty litter box.

Holding in urine can strain the kidneys, so maintaining litter box hygiene is crucial.

Cats often develop kidney failure around the age of six, so be vigilant about changes in daily water intake and urination amounts.

A decline in immunity also affects kidney health.

Immunity is a crucial factor in maintaining overall body balance, and a drop in immunity can lead to various diseases, not just kidney failure.

To help your pet lead a healthy and peaceful life, daily care is essential.
Cordy supplement holds the potential of supporting health by restoring the body’s self-regulating immunity.

For pets, such as dogs, cats, and exotics, suffering from conditions like tumors, Cordy can help reduce side effects from aggressive treatments and may assist in maintaining quality of life when no other options are available.

Moreover, there are cases where administering Cordy, which contains organic germanium, has improved kidney values through its blood circulation promoting effects.

If you have any questions, please feel free to contact us.

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

Let’s aim to coexist and improve while managing illness

Here’s the translation of the provided text to English:

]]>