Information provided by: Harumi Yasaka (Owner)

Species: Cat
Emu-chan (Male) Kuro-chan (Male)
Birthdate: May 1, 2019 (Estimated, as they were born on the balcony)
Weight: Emu-chan 6.3 kg, Kuro-chan 6.4 kg
Age: 5 years and 2 months
Condition: Feline Leukemia (both cats)

Progress and Current Condition

The veterinarian told me that there is no treatment for leukemia, so we should focus on preventing the onset and boosting their immunity.
While searching for supplements, I came across Cordy and informed the vet. They said it was a good idea, so we decided to try it.

Since the health checkup in May 2021 revealed the condition, we started using Cordy around June 2021. We could give it to them before any severe symptoms appeared.
Their weight increased by about 1 kg, and we transitioned them from outdoor to fully indoor cats. They remain as energetic and have the same good appetite, running around energetically.

Cordy is the only supplement they have been on for about three years.

● There are no medications from the animal hospital, as there is no treatment. We only manage symptoms when they appear.

● How we give Cordy
We used to form small balls and put them in their mouths three times a day or mix it with Churu, but recently we dissolve it in water and mix it into their food twice a day.

● Diet: We provide a balanced complete feed and avoid giving them too much Churu or snacks.

Emu-chan

Kuro-chan

● A final word from the owner
When they were diagnosed with leukemia, the vet told us there was an 80% chance they wouldn’t live past three years. Since they were two years old at the time, I was devastated thinking they had only one year left to live.
I believe the fact that they are still healthy and lively is thanks to Cordy. I have a reason to trust Cordy. Our cats have a friend, a so-called community cat who is completely an outdoor cat, and they played together since kittenhood.
This friend cat, who comes to our window healthy, has been fed the leftovers of our cats’ Cordy-infused food. Other outdoor cats usually disappear within three years, but this one has been thriving for five years.
Isn’t this thanks to Cordy? I believe that you don’t have to give up even with an illness. Thank you, and please continue to support us.

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

Our lab is researching whether administering Cordy can modulate immunity, maintain or improve Quality of Life (QOL), and be effective against cancer. If you have any questions, please contact us.

Information Provided By: Mika Shibue (Owner)

Species: Dog, Chihuahua
Gender: Male, Kuu-chan
Date of Birth: January 30, 2011 (13 years and 3 months old)
Weight: 3.4 kg (as of May 27, 2024)
Condition: Malignant Apocrine Gland Tumor

Progress and Current Condition

On January 30, 2022, surgery was performed on his birthday. The attending hospital had already notified us that there was a high possibility of metastasis and that the future outlook was uncertain.
In this desperate situation, I searched for ways to ensure he could live each day as pain-free and comfortably as possible and came across Cordy.

After about 3 to 4 months of using Cordy, he seemed to be more energetic than before.
His weight remained stable, his appetite did not decrease, and a dog who used to sleep most of the time started bringing toys and asking to go for walks.

According to the veterinarian, the malignant tumor appears to have been overcome. Although a new growth appeared, it was not identified as a tumor.

Cordy is administered with approximately 1.5 spoons (about 1.5g) divided into 4 to 5 doses.
Now, he is enjoying his daily life with his owner!

The hospital recommended using Sendan Alpha.

Diet
Dry food, sweet potato, chicken breast, pumpkin, etc.

At our laboratory, we are researching whether Cordy can modulate the immune system, maintain or improve the quality of life (QOL), and have an effect on cancer. If you have any questions, please contact us.

Information Provided By: Mari Yamamoto (Owner)

Species: Cat
Gender: Female, Mimi-chan
Age: Unknown (Rescued Cat) as of November 2022
Weight: 6.3kg
Condition: Lung tumor

Progress and Current Status

The tumor shrank and Mimi-chan is full of energy after two months of taking Cordy!

I discovered Cordy through an online search and decided to purchase a trial size.
After starting it in March 2023, the check-up two months later showed a significant reduction in the tumor size—what a surprise!

Her weight, energy levels, and appetite remained stable.

I gave her Cordy six to seven times a day, using the included spoon to form it into small balls, thanks to family support for the daily routine.

Medications from the hospital for coughing
Bromhexine 4mg, Theophylline

Diet
Doctor’s Care Urinary Care for Cats

監修獣医師：林美彩　　所属クリニック：chicoどうぶつ診療所

代替療法と西洋医学、両方の動物病院での勤務経験と多数のコルディの臨床経験をもつ。　モノリス在籍時には、一般的な動物医療（西洋医学）だけでは対応が困難な症例に対して多くの相談を受け、免疫の大切さを痛烈に実感する。
ペットたちの健康維持・改善のためには薬に頼った対処療法だけではなく、「普段の生活環境や食事を見直し、自宅でさまざまなケアを取り入れることで免疫力を維持し、病気にならない体づくりを目指していくことが大切である」という考えを提唱し普及活動に従事している。

所属：

• 獣医保健ソーシャルワーク協会

著書：

• 獣医師が考案した長生き犬ごはん 安心・簡単・作り置きOK!
• 獣医師が考案した長生き猫ごはん　安心・簡単・作り置きＯＫ！
• 獣医師が考案した一汁一菜長生き犬ごはん こだわりの安心レシピ&作り置きOK!

At our laboratory, we are researching whether Cordy can modulate the immune system, maintain or improve quality of life (QOL), and have potential effects on cancer. If you have any questions, please contact us.

The name “ACANA” is derived from the agricultural region of Alberta, Canada, and the food is made using truly “fresh” ingredients (using raw meat, raw vegetables, and fruits that are incorporated into the manufacturing process without freezing, heating, chemical substances, or preservatives).

ACANA’s concept of ‘Biologically Appropriate Pet Food’ is a food that replicates the natural diet of meat-eating dogs and cats, which originally preyed on herbivores.

・No artificial flavors, colors, or preservatives added in the kitchen
・No use of ingredients such as soy, corn, tapioca, or wheat in the kitchen

These points make it reliable for you to use.

Moreover, dogs and cats require protein even more than we do. ACANA uses about 60% of ingredients certified by the Canadian Food Inspection Agency, including chicken, flounder, or lamb, ensuring sufficient protein intake.

Additionally, all the carbohydrates used are of low GI. Avoiding the use of wheat and opting for gluten-free options leads to fewer allergies and also helps protect the digestive tract of dogs. Digestive health is a key to maintaining immunity, and because of low GI, it also helps to prevent blood sugar spikes and reduces vascular damage.

Dog Food
・Wild Coast Recipe, Prairie Poultry Recipe, Red Meat Recipe: Crude Protein 29%, Crude Fat 17%
・Puppy Small Breed Recipe, Puppy Recipe: Crude Protein 33%, Crude Fat 20%
・Puppy Large Breed Recipe: Crude Protein 33%, Crude Fat 15%
・Adult Small Breed Recipe: Crude Protein 31%, Crude Fat 17%
・Adult Large Breed Recipe, Free-Run Duck, Yorkshire Pork, Grass-Fed Lamb: Crude Protein 31%, Crude Fat 15%
・Sport & Agility Recipe: Crude Protein 35%, Crude Fat 22%
・Light & Fit Recipe: Crude Protein 35%, Crude Fat 11%
・Senior Recipe: Crude Protein 33%, Crude Fat 14%
・Wild Prairie Recipe, Pacifica Recipe, Grasslands Recipe, Ranchlands Recipe: Crude Protein 35%, Crude Fat 17%

Cat Food
・ORIGINAL CAT, REGIONAL RED, TUNDRA, KITTEN: Crude Protein 40%, Crude Fat 20%
・SIX FISH: Crude Protein 40%, Crude Fat 19%
・FIT & TRIM: Crude Protein 42%, Crude Fat 15%
・GUARDIAN8: Crude Protein 40%, Crude Fat 19%

ACANA’s dog and cat foods are high in protein compared to commercially available foods, making them not only ideal for maintaining health but also recommended for pets with tumors or diabetes looking to restrict carbohydrates.

However, one point to note is that ACANA products tend to be relatively high in fat. While fat is not inherently bad, in the case of dry food, ‘oxidation’ starts from the moment it is manufactured. Oxidized oil can cling to the insides of blood vessels and lymphatic vessels, impairing circulation, and it can also strain the liver, which metabolizes fats.

Therefore, we recommend using the product within 10 days after opening, so it might be better to purchase smaller packages. If only small amounts are consumed, we recommend dividing the contents into smaller portions, vacuum packing them, or placing them in a ziplock bag with an oxygen absorber and desiccant, storing them in a cool, dry place.

There are various types available, so rotating between small packages to avoid your pet getting bored with the taste might be a good idea.

Your pet’s body is built on what they eat every day. Please aim to maintain the health of your beloved dog or cat by incorporating various foods and homemade meals.

The heristo group is a leading company in the food industry, dealing with meat and fish. All of their products, whether for humans or pets, are manufactured under the same high-quality standards.

This means that the ingredients are ‘human grade,’ making them a safe option to feed your pets.

The ‘INTEGRA PROTECT’ line we handle is a therapeutic diet developed by Animonda in collaboration with veterinarians.

① Kidney Care

This is a therapeutic diet for managing chronic kidney disease (CKD).

By reducing the content of protein and phosphorus, it is expected to support kidney function.

Since it also does not contain ‘gluten,’ which can burden the intestines, it is suitable for pets that have weak stomachs as well as those with CKD.

Typically, there are limited options for kidney care food, but this kidney care wet food offers:

For dogs: 3 types – beef, pork, chicken

For cats: 6 types – beef, pork, chicken, turkey, duck, veal

Many pets with kidney disease have sensitive tastes and may get bored of the same flavor, so it’s helpful to have a variety to rotate through.

For dry food, it contains a high amount of fat for calorie supplementation. To avoid the burden on the body from oxidized fats, it is recommended to consume within 7-10 days after opening.

Initially within 6 months.

Before use and if you wish to extend the period, it is recommended to consult a veterinarian.

Dogs are closer to omnivorous carnivores and need to ingest sufficient protein.

“High-protein diet ≠ Kidney disease.” Therefore, this therapeutic diet should only be used for dogs that have been specifically diagnosed with kidney disease by a veterinarian (stage 3 or higher according to the IRIS classification, a marker for kidney disease).

If you are unsure about the stage of your pet’s kidney disease, please refer to the following URL and have your most recent blood test results on hand.

• Chronic Kidney Disease in Dogs and Cats (Japanese)

② Gastrointestinal Care

This is a therapeutic diet specially developed to manage acute diarrhea symptoms.

It uses hydrolyzed proteins to reduce the digestive burden.

Furthermore, it contains Yucca schidigera to prevent struvite.

Since an imbalanced intestinal environment can also cause urinary stones such as struvite, it is beneficial to be able to address both gastrointestinal health and urinary stones.

Up to 12 weeks.

Before use and if you wish to extend the period, it is recommended to consult a veterinarian.

③ Allergy Care

This is a therapeutic diet specifically developed for food allergies, containing only one type of animal protein, which is the cause of allergies.

For wet food, there are four types for both dogs and cats: turkey, horse, chicken, lamb. There’s also pork for cats only, so please choose the protein source that does not cause an allergic reaction.

3-8 weeks.

Before use and if you wish to extend the period, it is recommended to consult a veterinarian.

④ pH Care (Cats only)

This therapeutic diet is specially developed to make it difficult for urinary stones to form, supporting the maintenance of the urinary pH balance with a blend of minerals.

There are two types: one for struvite and one for calcium oxalate stones, so please choose based on the results of a urine test.

Initially within 6 months.

Before use and if you wish to extend the period, it is recommended to consult a veterinarian.

⑤ Diabetes Care (Cats only)

This is a therapeutic diet designed for diabetic pets, formulated with high protein and low carbohydrates to prevent rapid spikes in postprandial blood glucose levels.

A high protein and low carbohydrate diet is also recommended for pets with tumors, as it provides an appropriate nutritional balance. Therefore, it can also be used as food for pets with tumors.

There are six types: beef, poultry (chicken and turkey), chicken liver, rabbit, salmon, and turkey heart. It is recommended to rotate these options.

Initial period: within 6 months.

It is recommended to consult with a veterinarian before using this diet and if you plan to extend the usage period.

There is a note stating that all six types can be used indefinitely if symptoms improve. However, therapeutic diets are specifically designed to address certain diseases. Therefore, it is advisable to gradually transition to regular pet food or complete nutrition food as your pet’s condition stabilizes.

Therapeutic diets are akin to medications.

Do not incorporate or discontinue them based on your own judgment. Always consult with a veterinarian before making any changes.

CBD stands for Cannabidiol, one of the natural phytocannabinoid compounds extracted from the stems and seeds of hemp (Cannabis sativa).

Not only humans but also dogs and cats have a system called the ECS (Endocannabinoid System) to maintain health.

The hormones involved in this system are called ‘cannabinoids.’ These cannabinoids decrease due to stress and aging, leading to ‘cannabinoid deficiency syndrome,’ which can cause various health issues.

Causes of Cannabinoid Deficiency Syndrome:
– Genetics
– Unbalanced diet
– Lack of exercise
– Poor sleep quality (e.g., short sleep duration)
– Overuse of medication
– Chronic stress

Main Symptoms Suspected in Cannabinoid Deficiency Syndrome:
– Excessive barking and fearfulness
– Restlessness
– Lack of energy
– Difficulty sleeping
– Pain
– Joint problems
– Skin issues

CBD is proposed as a supplement to these cannabinoids. By acting on the ECS, CBD helps maintain homeostasis, thereby maintaining health from the inside out. In other words, CBD helps restore the body and mind to their ‘natural state.’

The Difference Between CBD and THC:
Hemp contains more than 100 types of phytocannabinoid compounds. They can be broadly divided into two categories: CBD and THC (Tetrahydrocannabinol).

CBD is a component extracted from the stems and seeds of hemp. It interacts with neurotransmitters such as serotonin and dopamine in the brain, aiding in calming effects and stress relief. It is characterized by its lack of dependency and toxicity, offering deep relaxation. Over 1,000 studies have been conducted, revealing its efficacy for various symptoms. It is also used as a medication overseas.

On the other hand, THC is a component extracted from the flowers, buds, leaves, and roots of hemp that acts on the mind. When inhaled, it can make one feel “high,” leading to dependency and toxicity, hence its use is prohibited by law.

Some low-quality CBD products may contain trace amounts of THC. Using such products, even unknowingly, is illegal. It is recommended to inquire with manufacturers and ensure safety and quality personally.

Differences in CBD Manufacturing Methods:
CBD raw materials come in three types based on the manufacturing method: ① Full Spectrum, ② Broad Spectrum, and ③ Isolate.

① Full Spectrum
Most natural composition but may contain trace amounts of THC, which is regulated in Japan.

② Broad Spectrum
Contains a combination of cannabinoids other than THC, terpenes, and flavonoids, believed to offer a broader range of therapeutic effects. The synergy of these compounds is expected to result in higher efficacy, known as the ‘entourage effect.’ Products from the pet CBD manufacturer CANNNIMAL fall into this category.

③ Isolate
Contains no THC, making it the primary type imported into Japan. “Isolate” refers to extracting a single cannabinoid component from over 100 types and dissolving it in coconut oil or other oils. CBD alone or a combination of isolated components like CBG and CBN are offered.

Potential Benefits of CBD:
By incorporating the cannabinoids contained in CBD into the body, it is expected to regulate the ECS, helping to care for various ailments.

Foreign studies report potential applications for the following symptoms:
– Anxiety relief and reduction of anxious behavior
– Reduction of neuroses: anti-seizure effects, alleviation of epilepsy symptoms, neuroprotection, neurodegenerative diseases
– Brain ischemia (reduced blood and oxygen supply to the brain)
– Myocardial ischemia (reduced blood and oxygen supply to the myocardium)
– Inflammation
– Psoriasis
– Inflammatory bowel disease
– Arthritis and associated pain
– Inflammation suppression (cytokine release inhibition)
– Vomiting: chemotherapy-induced vomiting, motion sickness
– Type 1 diabetes, diabetic retinopathy
– Promotion of fracture healing and bone regeneration
– Cancer cells: Induction of apoptosis, inhibition of cancer cell proliferation, suppression/reduction of metastasis, mitigation of chemotherapy side effects
– Kidney protection (Cisplatin, used in chemotherapy, is highly toxic to the kidneys)
– Inhibition of drug-resistant bacteria activity

(Source: Izzo, et al. “Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.” Trends in pharmacological sciences 30.10 (2009): 515-527.)

While we cannot guarantee that it will be effective for every pet’s specific condition, this is an alternative therapy well worth trying for those who:
– Want to care for vague or general health issues
– Prefer not to use too many medications
– Are at a standstill with current treatments and are looking for other options
– Wish to alleviate stress

In recent years, low-carb diets have become popular, and there is often a misconception that low-carb means restricting carbohydrates. However, strictly speaking, carbohydrates are not equivalent to sugars.

Carbohydrates are composed of sugars and dietary fiber. Both sugars and dietary fiber are very important nutrients.

However, for pets with tumors, it is crucial to choose the “type” of sugar carefully.

### Types of Sugars

Sugars can be classified based on the number of glucose molecules they contain: monosaccharides, disaccharides, trisaccharides, and polysaccharides.

**Types of Sugars:**

**1. Monosaccharides**
Glucose, fructose, and galactose

**2. Disaccharides**
Sucrose (table sugar) = glucose + fructose
Maltose = two glucose molecules
Lactose = glucose + galactose

**3. Trisaccharides**
Oligosaccharides

**4. Polysaccharides**
Starch, dextrin, glycogen, and sugar alcohols

One important point to consider when consuming these sugars is where they are broken down into glucose.

– **Monosaccharides and Disaccharides**
Monosaccharides and disaccharides turn into glucose in the small intestine. Once broken down into glucose, they are absorbed through the small intestine and used as an energy source in the body.

They are broken down and absorbed faster than fats, making them suitable for quickly replenishing energy and raising blood sugar levels during intense exercise or hypoglycemia.

However, glucose is not only the sole nutrient source for cancer cells (tumor cells) but also raises blood sugar levels, stimulating insulin secretion, which in turn promotes the occurrence, growth, and metastasis of cancer.

Stimulating insulin secretion also puts a burden on the pancreas, increasing the risk of diabetes when the pancreas becomes exhausted.

Additionally, AGEs (Advanced Glycation End-products) produced from “glyceraldehyde,” a metabolic product of fructose, are highly toxic and generate a lot of reactive oxygen species. This cell damage caused by reactive oxygen species may also increase cancer risk.

Moreover, glucose turns into neutral fat due to insulin, so excessive intake of glucose can lead to obesity.

Obesity can cause inflammation and various other symptoms, so it is important to be mindful of excessive glucose intake — particularly monosaccharides and disaccharides.

– **Oligosaccharides**
Oligosaccharides are not broken down by enzymes but are decomposed and utilized as food by beneficial bacteria such as bifidobacteria and butyrate-producing bacteria in the large intestine. When beneficial bacteria increase, they produce short-chain fatty acids like acetic acid, butyric acid, and propionic acid.

The production of fatty acids causes the intestinal environment to become slightly acidic, inhibiting the activity of harmful bacteria and activating intestinal peristalsis, thereby improving the intestinal environment.

Butyric acid is expected to act on regulatory T cells (Treg), which are involved in autoimmune diseases, to help prevent the immune system from running amok.

Supporting beneficial bacteria with oligosaccharides can consequently lead to increased short-chain fatty acid production, essential for improving the intestinal environment.

Various types of oligosaccharides include isomalt oligosaccharides, fructooligosaccharides, xylooligosaccharides, galactooligosaccharides, soybean oligosaccharides, milk oligosaccharides, raffinose (beet oligosaccharide), and kestose (an extract from oligosaccharides that selectively provides nutrients to beneficial bacteria like bifidobacteria).

Be cautious when buying commercially available oligosaccharides, as they may contain other sugars like glucose-fructose syrup. Always check the ingredients.

– **Polysaccharides**
Polysaccharides have a structure containing many monosaccharides, so they take longer to break down, resulting in a more gradual absorption.

Therefore, they do not cause a rapid rise in blood sugar levels like monosaccharides, but they still eventually break down into monosaccharides, leading to obesity if consumed excessively.

Among the polysaccharides, starch known as “resistant starch” is not digested in the small intestine and reaches the large intestine, where it activates intestinal bacteria, improves constipation, and helps prevent rapid blood sugar spikes. Because it has properties of both insoluble and soluble fiber, it is sometimes referred to as a hyper-fiber or comfortable starch.
Resistant starch is found in legumes, grains, and tubers. When these foods are cooked and gelatinized (converted to alpha-starch), they become digestible and can cause an increase in blood glucose levels. However, by cooling them again, the starch recrystallizes and becomes less digestible, effectively turning into fiber.

Since legumes, grains, and tubers also contain other carbohydrates, it’s important not to consume them in excess. However, they do serve as a source of resistant starch.

A deficiency in dietary fiber can also lead to a deterioration in gut health. Therefore, when incorporating these foods into your diet, keep the portions small and make sure to cool them after cooking before consumption.

Among grains, a new variety called “BarleyMax” has been developed to have a higher content of resistant starch, so using this grain might be beneficial.

There are various types of carbohydrates, so it is vital to understand which ones to limit when it comes to ‘carbohydrate restriction.’

For pets with tumors, it is important to minimize carbohydrate intake as much as possible, but optimizing gut health is also a fast track to stabilizing the immune system. This might involve actively incorporating oligosaccharides in their diet. Additionally, using low-GI carbohydrate sources can be beneficial as an energy and calorie source.

Do check the amount of carbohydrates and fiber in the food your pet usually eats and use this information to review and improve their daily diet.

【Feline Coronavirus Infection】
This infection is caused by Feline Enteric Coronavirus (FECV), one of the Feline Coronaviruses (FCoV), and is also known as ‘Feline Enteric Coronavirus Infection‘. The prevalence of FECV in domestic cats is very high, with rates around 40% in wild cats and about 90% in multi-cat households. Therefore, it’s safe to assume that most cats adopted from breeders or pet shops carry FECV.

＜Symptoms＞
In most cases, pathogenic symptoms do not appear. If symptoms do occur, they are usually mild diarrhea.

＜Route of Infection＞
As the virus infects the intestinal tract, it can easily spread through feces and infect via the mouth or nose. Normally, the infection is transient, and antibody levels decrease over time.

＜Diagnosis Method＞
There are two types of tests: antibody tests and PCR tests. Both are conducted by sending samples to a testing center.

＜Treatment＞
Since most FECV cases are asymptomatic, treatment is typically supportive if diarrhea symptoms are present.

＜Precautions＞
In the case of FCoV, it loses infectivity at room temperature within minutes to hours and can usually be inactivated with common alcohol or hypochlorite disinfectants. However, the virus in feces can be protected by proteins in the feces and remain resistant in the environment for 3 to 7 weeks. Therefore, frequent cleaning and disinfection of living environments, litter boxes, and dishes are important.

＜Prevention＞
As there is no vaccine to prevent Feline Coronavirus, avoiding contact with infected cats is the best prevention. However, given the high prevalence in domestic cats, avoiding contact with infected cats can be challenging. Prior testing to confirm negativity before bringing a new cat into the home and keeping cats indoors can help reduce the risk. Additionally, humans may transmit the virus to cats, so after contact with an infected cat, change clothes, disinfect hands (or ideally shower), before touching your own cat.

＜Relationship with Feline Infectious Peritonitis (FIP)＞
Feline Infectious Peritonitis (FIP) is also a type of Feline Coronavirus (FCoV). It is believed FECV can mutate into Feline Infectious Peritonitis Virus (FIPV) under certain conditions, leading to the development of FIP. For more information on FIP, please refer to this page.

● For information on FIP treatment methods, please refer to this page.

【Feline Herpesvirus Infection】
This infection is caused by feline herpesvirus type 1 (FeHV-1) and is also known as “feline viral rhinotracheitis.”
Together with feline calicivirus and feline chlamydia, it forms part of upper respiratory infections, commonly referred to as “cat flu.”

＜Symptoms＞
Nasal discharge
Continuous sneezing
Eye discharge
Conjunctivitis and keratitis
Stomatitis
Loss of appetite
Fever

Conjunctivitis is typically present in both eyes, and in severe cases, eyeball rupture can occur. If stomatitis worsens, there may be increased drooling and strong bad breath. Severe cases are also at a higher risk of developing pneumonia.

In young kittens or cats with weakened immune systems, secondary bacterial infections or mixed infections can exacerbate the symptoms.

＜Transmission Routes＞
The virus is transmitted nasally or orally through nasal discharge, eye discharge, and saliva from infected cats. Moreover, since herpesvirus can remain latent in the trigeminal ganglion, infected cats can harbor the virus for life. Even if the symptoms appear to resolve completely, a decrease in immunity can cause the herpesvirus in the trigeminal ganglion to reactivate, leading to new symptoms and making the cat a source of infection again.

＜Diagnosis Methods＞
There are several diagnostic methods, including serological tests (virus neutralization tests, indirect immunofluorescence assay), virus isolation, and PCR tests. Virus isolation is considered the most reliable method.

＜Treatment Methods＞
There is no effective treatment for herpesvirus itself; thus, supportive care aims to alleviate current symptoms and allow the cat to recover using its own strength and immune system.

Supportive care may include fluid therapy to correct dehydration, nutritional support, administration of non-steroidal anti-inflammatory drugs to alleviate pain and inflammation, and administration of interferon.

Recently, new antiviral eye drops that target and disrupt the replication of the herpesvirus DNA have become available. Oral administration of L-lysine is also believed to be effective, and it may be beneficial to take it as a supplement.

In addition, broad-spectrum antibiotics may be used to prevent secondary bacterial infections or mixed infections as previously mentioned.

＜Precautions＞
FeHV-1 can be easily killed by most commercial disinfectants (such as alcohol-based disinfectants) and detergents. However, because it can remain latently infected inside the body, disinfecting the living environment, including toilets and dishes, cannot eliminate the virus within the cat. Maintaining usual hygiene and minimizing stress can help prevent recurrence.

＜Prevention Methods＞
FeHV-1 prevention is possible with vaccination. Ensuring kittens are properly vaccinated can help prevent the disease, though it may not completely prevent infection. To avoid immune imbalance, it’s important to minimize stress and consider supplements that support immune health, which may help in preventing the onset of the disease.